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Search results
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2017
Cytokine-Induced MMP13 Expression in Human Chondrocytes is dependent on Activating Transcription Factor 3 (ATF3) regulation
Chan, C. M., Macdonald, C. D., Litherland, G., Wilkinson, D. J., Skelton, A., Europe-Finner, G. N. & Rowan, A. D., 3 Feb 2017, In: Journal of Biological Chemistry. 292, 5, p. 1625-1636 12 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Link opens in a new tab Citations (Scopus) -
2014
Glycogen Synthase Kinase 3 Inhibition Stimulates Human Cartilage Destruction and Exacerbates Murine Osteoarthritis
Litherland, G. J., Hui, W., Elias, M. S., Wilkinson, D. J., Watson, S., Huesa, C., Young, D. A. & Rowan, A. D., Aug 2014, In: Arthritis & Rheumatology. 66, 8, p. 2175-2187 13 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Link opens in a new tab Citations (Scopus) -
2013
The role of protein kinase D signalling in the induction of matrix metalloproteinases in human articular chondrocytes
Baker, J., Litherland, G. J. & Rowan, A. D., Apr 2013, In: Rheumatology. 52, S1, p. S49-S49 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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2012
Glycogen synthase kinase-3 as a gatekeeper of human cartilage degradation
Litherland, G. J., Elias, M. S., Curtis, H. & Rowan, A. D., 1 Aug 2012, In: International Journal of Experimental Pathology. 93, 4, p. A31-A31Research output: Contribution to journal › Meeting Abstract › peer-review
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Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases
Hui, W., Litherland, G. J., Elias, M. S., Kitson, G. I., Cawston, T. E., Rowan, A. D. & Young, D. A., Mar 2012, In: Annals of the Rheumatic Diseases. 71, 3, p. 455-62 8 p.Research output: Contribution to journal › Article › peer-review
170 Link opens in a new tab Citations (Scopus) -
2010
HDAC-mediated control of ERK- and PI3K-dependent TGF-beta-induced extracellular matrix-regulating genes
Barter, M. J., Pybus, L., Litherland, G. J., Rowan, A. D., Clark, I. M., Edwards, D. R., Cawston, T. E. & Young, D. A., Sept 2010, In: Matrix Biology. 29, 7, p. 602-612Research output: Contribution to journal › Article › peer-review
72 Link opens in a new tab Citations (Scopus) -
Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibition of the P38 mitogen-activated protein kinase pathway
Hui, W., Litherland, G. J., Jefferson, M., Barter, M. J., Elias, M. S., Cawston, T. E., Rowan, A. D. & Young, D. A., Nov 2010, In: Rheumatology. 49, 11, p. 2043-2053Research output: Contribution to journal › Article › peer-review
45 Link opens in a new tab Citations (Scopus) -
Protein Kinase C Isoforms zeta and iota Mediate Collagenase Expression and Cartilage Destruction via STAT3-and ERK-dependent c-fos Induction
Litherland, G. J., Elias, M. S., Hui, W., Macdonald, C. D., Catterall, J. B., Barter, M. J., Farren, M. J., Jefferson, M. & Rowan, A. D., 16 Jul 2010, In: Journal of Biological Chemistry. 285, 29, p. 22414-22425Research output: Contribution to journal › Article › peer-review
Open Access46 Link opens in a new tab Citations (Scopus) -
2009
Role of protein kinase C isoforms in collagenase induction and cartilage degradation
Rowan, A. D. & Litherland, G., 2009, In: Osteoarthritis and Cartilage. 17, Supplement 1, p. S146Research output: Contribution to journal › Meeting Abstract
Open Access -
2008
Differential Toll-like receptor-dependent collagenase expression in chondrocytes
Zhang, Q., Hui, W., Litherland, G. J., Barter, M. J., Davidson, R., Darrah, C., Donell, S. T., Clark, I. M., Cawston, T. E., Robinson, J. H., Rowan, A. D. & Young, D. A., Nov 2008, In: Annals of the Rheumatic Diseases. 67, 11, p. 1633-1641Research output: Contribution to journal › Article › peer-review
83 Link opens in a new tab Citations (Scopus) -
Metalloproteases as potential therapeutic targets in arthritis treatment
Rowan, A. D., Litherland, G. J., Hui, W. & Milner, J. M., Jan 2008, In: Expert Opinion on Therapeutic Targets. 12, 1, p. 1-18 18 p.Research output: Contribution to journal › Article › peer-review
63 Link opens in a new tab Citations (Scopus) -
Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signaling-dependent
Litherland, G. J., Dixon, C., Lakey, R. L., Robson, T., Jones, D., Young, D. A., Cawston, T. E. & Rowan, A. D., 23 May 2008, In: Journal of Biological Chemistry. 283, 21, p. 14221-14229 9 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Link opens in a new tab Citations (Scopus)