Abstract
Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.
| Original language | English |
|---|---|
| Pages (from-to) | 1560-2 |
| Number of pages | 3 |
| Journal | British Journal of Cancer |
| Volume | 73 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Jun 1996 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Acute-Phase Reaction
- Aged
- Aged, 80 and over
- Carcinoma, Non-Small-Cell Lung
- Female
- Humans
- Interleukin-6
- Lung Neoplasms
- Male
- Middle Aged
- Weight Loss
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