The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

H.R. Scott, D.C. McMillan, A. Crilly, C.S. McArdle, R. Milroy

Research output: Contribution to journalArticle

Abstract

Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.

Original languageEnglish
Pages (from-to)1560-2
Number of pages3
JournalBritish Journal of Cancer
Volume73
Issue number12
DOIs
Publication statusPublished - Jun 1996
Externally publishedYes

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Non-Small Cell Lung Carcinoma
Weight Loss
Interleukin-6
C-Reactive Protein
Acute-Phase Reaction
Albumins
Blood Platelets
Weights and Measures

Keywords

  • Acute-Phase Reaction
  • Aged
  • Aged, 80 and over
  • Carcinoma, Non-Small-Cell Lung
  • Female
  • Humans
  • Interleukin-6
  • Lung Neoplasms
  • Male
  • Middle Aged
  • Weight Loss

Cite this

Scott, H.R. ; McMillan, D.C. ; Crilly, A. ; McArdle, C.S. ; Milroy, R. / The relationship between weight loss and interleukin 6 in non-small-cell lung cancer. In: British Journal of Cancer. 1996 ; Vol. 73, No. 12. pp. 1560-2.
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The relationship between weight loss and interleukin 6 in non-small-cell lung cancer. / Scott, H.R.; McMillan, D.C.; Crilly, A.; McArdle, C.S.; Milroy, R.

In: British Journal of Cancer, Vol. 73, No. 12, 06.1996, p. 1560-2.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

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AU - McMillan, D.C.

AU - Crilly, A.

AU - McArdle, C.S.

AU - Milroy, R.

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AB - Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.

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KW - Carcinoma, Non-Small-Cell Lung

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