The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

H.R. Scott; D.C. McMillan; A. Crilly; C.S. McArdle; R. Milroy

doi:10.1038/bjc.1996.294

The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

H.R. Scott, D.C. McMillan, A. Crilly, C.S. McArdle, R. Milroy

Research output: Contribution to journal › Article › peer-review

152 Citations (Scopus)

Abstract

Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.

Original language	English
Pages (from-to)	1560-2
Number of pages	3
Journal	British Journal of Cancer
Volume	73
Issue number	12
DOIs	https://doi.org/10.1038/bjc.1996.294
Publication status	Published - Jun 1996
Externally published	Yes

Keywords

Acute-Phase Reaction
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung
Female
Humans
Interleukin-6
Lung Neoplasms
Male
Middle Aged
Weight Loss

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/bjc.1996.294

Cite this

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title = "The relationship between weight loss and interleukin 6 in non-small-cell lung cancer",

abstract = "Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.",

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author = "H.R. Scott and D.C. McMillan and A. Crilly and C.S. McArdle and R. Milroy",

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T1 - The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

AU - Scott, H.R.

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AU - Crilly, A.

AU - McArdle, C.S.

AU - Milroy, R.

PY - 1996/6

Y1 - 1996/6

N2 - Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.

AB - Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.

KW - Acute-Phase Reaction

KW - Aged

KW - Aged, 80 and over

KW - Carcinoma, Non-Small-Cell Lung

KW - Female

KW - Humans

KW - Interleukin-6

KW - Lung Neoplasms

KW - Male

KW - Middle Aged

KW - Weight Loss

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JO - British Journal of Cancer

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ER -

The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

Abstract

Keywords

UN SDGs

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