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The effects of non-therapeutic anabolic androgenic steroid (AAS) use on cardiac structure and function

  • Fergal M. Grace*
  • , Nick Sculthorpe
  • , Julien S. Baker
  • , Lon Kilgore
  • *Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    Studies investigating the effects of Anabolic Androgenic Steroids (AAS) on the cardiovascular system have been present in the medical literature over the past forty years. The present chapter reviews the available literature on the impact that AAS use has on cardiovascular structure and function from the more popular studies in the 1980s, investigating the effects of AAS on cholesterol levels to the more currently popular studies that aim to identify the underlying mechanisms behind remodeling of cardiac muscle. There is currently good progress being made in understanding the physiological mechanisms behind AAS induced cardio-toxicity from both the in vitro and animal model. If current rates of progress are continued and the medical research community continues to publish both controlled and case studies then a clearer understanding of the mechanisms behind cardiovascular problems resulting from AAS use are expected in the near future.

    Original languageEnglish
    Title of host publicationPerspectives on Anabolic Androgenic Steroids (AAS) and Doping in Sport and Health
    EditorsFergal Grace
    PublisherNova Science Publishers, Inc.
    Chapter4
    Pages79-103
    Number of pages25
    ISBN (Electronic)9781620812617
    ISBN (Print)9781620812433
    Publication statusPublished - 31 Jul 2012

    Publication series

    NameSports and Athletics Preparation, Performance, and Psychology, Substance Abuse Assessment, Interventions and Treatment
    PublisherNova Science Publishers, Inc.

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