Activities per year
Abstract
High-intensity intermittent training (HIIT) has been shown to reduce the risk of chronic conditions including the development of type 2 diabetes mellitus (T2DM). Independently, a low vitamin D status has also been linked to the prevalence of T2DM. The aim of this study was to investigate if there was a synergistic metabolic effect of HIIT and vitamin D supplementation on glycemic control. A total of 20 male and female participants (age, 34 ± 9 year; BMI, 31.4 ± 2.8 kg·m −2 ) completed 6 weeks HIIT, and were randomized to ingest 100 μg·day -1 of vitamin D 3 or placebo. Response to an oral glucose tolerance test (OGTT) was determined at baseline and at 72 h postintervention. Glucose tolerance was improved as a result of the HIIT intervention, shown through a reduction in glucose and insulin concentrations during the OGTT, accompanied by a decrease in glucose (829 ± 110 to 786 ± 139 mmol·h −1 ·L −1 ; P = 0.043) and insulin (8101 ± 4755–7024 ± 4489 mU·h −1 ·L −1 ; P = 0.049) area under the curve (AUC). Supplementation increased 25-hydroxyvitamin D 3 concentration by 120% to a sufficiency status (P < 0.001). However, the consumption of vitamin D 3 seemed to attenuate the glucose response during an OGTT. Triglyceride content was lowered following the intervention (P = 0.025). There was no effect of the intervention on insulin sensitivity (IS) indices: ISI M atsuda and HOMA-IR. Our findings demonstrate that HIIT improves glucose tolerance in nondiabetic overweight and obese adults; however vitamin D 3 supplementation did not proffer any additional positive effects on the measured indices of metabolic health.
Original language | English |
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Article number | e13684 |
Number of pages | 12 |
Journal | Physiological Reports |
Volume | 6 |
Issue number | 9 |
DOIs | |
Publication status | Published - 30 Apr 2018 |
Externally published | Yes |
Keywords
- Glucose tolerance
- High-intensity intermittent training
- Vitamin D
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Dive into the research topics of 'The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults'. Together they form a unique fingerprint.Activities
- 1 Participation in conference
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Cell Symposia: Exercise Metabolism
Hannah Lithgow (Speaker)
2017Activity: Participating in or organising an event › Participation in conference