Synthesis and antifungal activity of novel aza–D–homosteroids, hydroisoquinolines, pyridines and dihydropyridines

G.L. Patrick; O.S. Kinsman

doi:10.1016/0223-5234(96)89557-2

Synthesis and antifungal activity of novel aza–D–homosteroids, hydroisoquinolines, pyridines and dihydropyridines

G.L. Patrick, O.S. Kinsman

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

A series of novel aza-d--homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and tetrahydropyridines were also tested. Several compounds showed a broad spectrum of modest antifungal activity and three structures were investigated further for fungicidal and in vivo activity

Original language	English
Pages (from-to)	615-624
Number of pages	10
Journal	European Journal of Medicinal Chemistry
Volume	31
Issue number	7-8
DOIs	https://doi.org/10.1016/0223-5234(96)89557-2
Publication status	Published - 1996
Externally published	Yes

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10.1016/0223-5234(96)89557-2

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title = "Synthesis and antifungal activity of novel aza–D–homosteroids, hydroisoquinolines, pyridines and dihydropyridines",

abstract = "A series of novel aza-d--homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and tetrahydropyridines were also tested. Several compounds showed a broad spectrum of modest antifungal activity and three structures were investigated further for fungicidal and in vivo activity",

author = "G.L. Patrick and O.S. Kinsman",

year = "1996",

doi = "10.1016/0223-5234(96)89557-2",

language = "English",

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pages = "615--624",

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T1 - Synthesis and antifungal activity of novel aza–D–homosteroids, hydroisoquinolines, pyridines and dihydropyridines

AU - Patrick, G.L.

AU - Kinsman, O.S.

PY - 1996

Y1 - 1996

N2 - A series of novel aza-d--homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and tetrahydropyridines were also tested. Several compounds showed a broad spectrum of modest antifungal activity and three structures were investigated further for fungicidal and in vivo activity

AB - A series of novel aza-d--homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and tetrahydropyridines were also tested. Several compounds showed a broad spectrum of modest antifungal activity and three structures were investigated further for fungicidal and in vivo activity

U2 - 10.1016/0223-5234(96)89557-2

DO - 10.1016/0223-5234(96)89557-2

M3 - Article

VL - 31

SP - 615

EP - 624

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

IS - 7-8

ER -

Synthesis and antifungal activity of novel aza–D–homosteroids, hydroisoquinolines, pyridines and dihydropyridines

Abstract

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