Synthesis and antifungal activity of novel aza–D–homosteroids, hydroisoquinolines, pyridines and dihydropyridines

G.L. Patrick, O.S. Kinsman

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

A series of novel aza-d--homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and tetrahydropyridines were also tested. Several compounds showed a broad spectrum of modest antifungal activity and three structures were investigated further for fungicidal and in vivo activity
Original languageEnglish
Pages (from-to)615-624
Number of pages10
JournalEuropean Journal of Medicinal Chemistry
Volume31
Issue number7-8
DOIs
Publication statusPublished - 1996
Externally publishedYes

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