Keyphrases
Cartilage
100%
Oncostatin M
100%
Collagenolysis
100%
Collagenase
100%
Phosphatidylinositol 3-kinase/Akt Signaling
100%
Phosphatidylinositol 3-kinase Signaling
80%
Matrix Metalloproteinase 13 (MMP13)
60%
Matrix metalloproteinase-1 (MMP-1)
60%
Catabolism
40%
Inflammatory Joint Disease
40%
Human Chondrocytes
40%
Akt Phosphorylation
40%
Kinase Cascade
40%
Cartilage Destruction
20%
Matrix Metalloproteinases
20%
Collagenolytic Activity
20%
Phosphoinositide 3-kinase (PI3K)
20%
Soluble Receptor
20%
Interleukin-6
20%
Excessive Extracellular Matrix
20%
Cell Behavior
20%
Small Interfering RNA (siRNA)
20%
Extracellular Matrix Remodeling
20%
New Drug Targets
20%
PDK1
20%
Synergistic Induction
20%
Phosphatidylinositol 3-kinase Pathway
20%
P110δ
20%
LY294002
20%
Loss Function
20%
P110
20%
Small Molecule Inhibitors
20%
AKT3
20%
Cartilage Extracellular Matrix
20%
Leukemia Inhibitory Factor
20%
AKT1
20%
Medicine and Dentistry
Collagenase
100%
Phosphoinositide 3-Kinase
100%
Collagen Degradation
100%
Akt Signaling
100%
Oncostatin M
71%
Kinase Signaling
57%
Collagenase 3
42%
Interstitial Collagenase
42%
Extracellular Matrix
42%
Protein Kinase B
42%
Arthropathy
28%
Cell Signaling Pathway
28%
Chondrocyte
28%
Matrix Metalloproteinase
14%
Interleukin 6
14%
Leukemia Inhibitory Factor
14%
Cytokine
14%
Cell Function
14%
Receptor
14%
LY294002
14%
Small Interfering RNA
14%
Phosphoinositide Dependent Protein Kinase 1
14%
Messenger RNA
14%
Biochemistry, Genetics and Molecular Biology
Collagenase
100%
Collagen Degradation
100%
Phosphoinositide 3-Kinase
100%
Akt Signaling
100%
Oncostatin M
71%
Matrix Metalloproteinase
57%
Interstitial Collagenase
42%
Protein Kinase B
42%
Chondrocyte
28%
Cytokine
14%
Small Interfering RNA
14%
Cell Function
14%
Phosphoinositide-Dependent Kinase-1
14%
Small Molecule
14%
Leukemia Inhibitory Factor
14%
LY294002
14%
Interleukin 6
14%
Messenger RNA
14%
Immunology and Microbiology
Collagen Degradation
100%
Cartilage
100%
Oncostatin M
100%
Akt Signaling
100%
Extracellular Matrix
60%
Arthropathy
40%
Chondrocyte
40%
P110δ
40%
Cell Function
20%
Cytokine
20%
Leukemia Inhibitory Factor
20%
Interleukin 6
20%
Pharmacology, Toxicology and Pharmaceutical Science
Collagenase
100%
Phosphatidylinositol 3 Kinase
100%
Protein Kinase B
100%
Oncostatin M
71%
Collagenase 3
42%
Interstitial Collagenase
42%
Arthropathy
28%
Cytokine
14%
Small Interfering RNA
14%
Phosphoinositide Dependent Protein Kinase 1
14%
Matrix Metalloproteinase
14%
Leukemia Inhibitory Factor
14%
Receptor
14%
2 Morpholino 8 Phenylchromone
14%
Interleukin 6
14%
Messenger RNA
14%