Surface modification to improve biocompatibility

M. Yaseen, F. Pan, X. Zhao, J.R. Lu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Significant progress has been made over the past few decades in the development of biomaterials. With our knowledge ever improving, the concept of surface biocompatibility has become drastically evolved. Current understanding of surface biocompatibility is well supported by mechanistic processes at molecular and cellular level. Through a select list of exemplar cases of surface modifications and characterization of cell responses, this article aims to place surface biocompatibility in the context of well-corroborated molecular and cellular interactions across the interface between live tissue and nonliving materials. Such concerted studies will ultimately lead to the development of artificial surfaces that offer fuller functionality and that could become better disguised under the host detection.
Original languageEnglish
Title of host publicationComprehensive Biotechnology
EditorsMurray Moo-Young
PublisherElsevier B.V.
Chapter36
Pages471-487
Number of pages17
Edition3rd
ISBN (Electronic)9780444640475
ISBN (Print)9780444640468
DOIs
Publication statusPublished - 23 Jul 2019
Externally publishedYes

Keywords

  • Biocompatibility
  • Biomaterials
  • Cell interactions
  • Protein structure
  • Surface modification

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  • Cite this

    Yaseen, M., Pan, F., Zhao, X., & Lu, J. R. (2019). Surface modification to improve biocompatibility. In M. Moo-Young (Ed.), Comprehensive Biotechnology (3rd ed., pp. 471-487 ). Elsevier B.V.. https://doi.org/10.1016/B978-0-444-64046-8.00276-7