Species variation in the metabolism of 15,16-dihydro-11-methylcyclopenta[a]phenanthren-17-one to its 3,4-dihydrodiol, the proximate carcinogen

Keyphrases

• Metabolism 100%
• Carcinogen 100%
• Dihydrodiol 100%
• Species Variation 100%
• Mass Spectrometry 33%
• Active Sites 33%
• In Vitro Metabolism 33%
• Benzo(a)pyrene 33%
• Methyl 33%
• Microsomal Preparation 33%
• Cytochrome P450 1A1 (CYP1A1) 33%
• Mouse Skin 33%
• Methyl Groups 33%
• Ultra-high Performance Liquid Chromatography (UHPLC) 33%
• Monkey 33%
• Five-membered Rings 33%
• Hamster 33%
• Retention Time 33%
• Synthetic Specimens 33%
• Time-frequency Spectrum 33%
• Ultraviolet Spectrum 33%
• Ethyl Acetate 33%
• Oxidative Enzymes 33%
• Molecular Model 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Phenanthrene 100%
• Carcinogen 100%
• Benzo(a)pyrene 33%
• Methyl Group 33%
• Cytochrome P450 1A1 33%
• Acetic Acid Ethyl Ester 33%
• Leporidae 33%
• Hyperbarism 33%
• Haplorhini 33%
• Oxidoreductase 33%

Chemistry

• Metabolite 100%
• Carcinogenic 25%
• Methyl Group 25%
• Benzo[a]pyrene 25%
• Ethyl Acetate 25%
• Mass Spectrometry 25%
• Retention Time 25%
• Ultraviolet Spectrum 25%
• High-Pressure Liquid Chromatography 25%
• Molecular Model 25%
• Cytochrome P450 25%