Socially-induced changes in sodium regulation affect the uptake of waterborne copper and silver in the rainbow trout, Oncorhynchus mykiss

K. A. Sloman, T.P. Morgan, D.G. McDonald, C.M. Wood

Research output: Contribution to journalArticle

Abstract

Subordinate fish take up more copper during water-borne exposure than dominant fish and consequently display higher tissue burdens. The present study demonstrated a similar effect of social status on water-borne silver uptake. We evaluated whether differences in copper and silver accumulation between individuals could be due to differences in metabolic rate, internal concentrations of cortisol or sodium uptake rates. In the absence of social interaction, experimentally increased metabolic rates (via moderate exercise) and elevated whole body cortisol concentrations (via feeding of a cortisol-spiked diet) did not result in increased metal uptake. However, elimination of the difference in sodium uptake rates between dominant and subordinate fish by exposing them to a saturating level of water-borne sodium (50 mM) resulted in an elimination of copper uptake differences. No significant differences in sodium and silver uptake rates were seen between dominant and subordinate fish exposed to elevated silver concentrations. Therefore, it appears that socially-mediated differences in copper and silver accumulation are a result of differences in sodium uptake rates as both silver and copper are known to cross the gill epithelia via sodium transport pathways.
Original languageEnglish
Pages (from-to)393-403
Number of pages11
JournalComparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Volume135
Issue number4
DOIs
Publication statusPublished - Aug 2003
Externally publishedYes

Fingerprint

Oncorhynchus mykiss
Silver
Copper
Sodium
Fish
Fishes
Hydrocortisone
Water
Interpersonal Relations
Nutrition
Epithelium
Metals
Tissue
Diet

Keywords

  • Apical sodium channel
  • Copper
  • Cortisol
  • Dominance
  • Gills
  • Silver
  • Sodium uptake rates
  • Respirometry

Cite this

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title = "Socially-induced changes in sodium regulation affect the uptake of waterborne copper and silver in the rainbow trout, Oncorhynchus mykiss",
abstract = "Subordinate fish take up more copper during water-borne exposure than dominant fish and consequently display higher tissue burdens. The present study demonstrated a similar effect of social status on water-borne silver uptake. We evaluated whether differences in copper and silver accumulation between individuals could be due to differences in metabolic rate, internal concentrations of cortisol or sodium uptake rates. In the absence of social interaction, experimentally increased metabolic rates (via moderate exercise) and elevated whole body cortisol concentrations (via feeding of a cortisol-spiked diet) did not result in increased metal uptake. However, elimination of the difference in sodium uptake rates between dominant and subordinate fish by exposing them to a saturating level of water-borne sodium (50 mM) resulted in an elimination of copper uptake differences. No significant differences in sodium and silver uptake rates were seen between dominant and subordinate fish exposed to elevated silver concentrations. Therefore, it appears that socially-mediated differences in copper and silver accumulation are a result of differences in sodium uptake rates as both silver and copper are known to cross the gill epithelia via sodium transport pathways.",
keywords = "Apical sodium channel, Copper, Cortisol, Dominance, Gills, Silver, Sodium uptake rates, Respirometry",
author = "Sloman, {K. A.} and T.P. Morgan and D.G. McDonald and C.M. Wood",
year = "2003",
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TY - JOUR

T1 - Socially-induced changes in sodium regulation affect the uptake of waterborne copper and silver in the rainbow trout, Oncorhynchus mykiss

AU - Sloman, K. A.

AU - Morgan, T.P.

AU - McDonald, D.G.

AU - Wood, C.M.

PY - 2003/8

Y1 - 2003/8

N2 - Subordinate fish take up more copper during water-borne exposure than dominant fish and consequently display higher tissue burdens. The present study demonstrated a similar effect of social status on water-borne silver uptake. We evaluated whether differences in copper and silver accumulation between individuals could be due to differences in metabolic rate, internal concentrations of cortisol or sodium uptake rates. In the absence of social interaction, experimentally increased metabolic rates (via moderate exercise) and elevated whole body cortisol concentrations (via feeding of a cortisol-spiked diet) did not result in increased metal uptake. However, elimination of the difference in sodium uptake rates between dominant and subordinate fish by exposing them to a saturating level of water-borne sodium (50 mM) resulted in an elimination of copper uptake differences. No significant differences in sodium and silver uptake rates were seen between dominant and subordinate fish exposed to elevated silver concentrations. Therefore, it appears that socially-mediated differences in copper and silver accumulation are a result of differences in sodium uptake rates as both silver and copper are known to cross the gill epithelia via sodium transport pathways.

AB - Subordinate fish take up more copper during water-borne exposure than dominant fish and consequently display higher tissue burdens. The present study demonstrated a similar effect of social status on water-borne silver uptake. We evaluated whether differences in copper and silver accumulation between individuals could be due to differences in metabolic rate, internal concentrations of cortisol or sodium uptake rates. In the absence of social interaction, experimentally increased metabolic rates (via moderate exercise) and elevated whole body cortisol concentrations (via feeding of a cortisol-spiked diet) did not result in increased metal uptake. However, elimination of the difference in sodium uptake rates between dominant and subordinate fish by exposing them to a saturating level of water-borne sodium (50 mM) resulted in an elimination of copper uptake differences. No significant differences in sodium and silver uptake rates were seen between dominant and subordinate fish exposed to elevated silver concentrations. Therefore, it appears that socially-mediated differences in copper and silver accumulation are a result of differences in sodium uptake rates as both silver and copper are known to cross the gill epithelia via sodium transport pathways.

KW - Apical sodium channel

KW - Copper

KW - Cortisol

KW - Dominance

KW - Gills

KW - Silver

KW - Sodium uptake rates

KW - Respirometry

U2 - 10.1016/S1532-0456(03)00139-X

DO - 10.1016/S1532-0456(03)00139-X

M3 - Article

VL - 135

SP - 393

EP - 403

JO - Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

JF - Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

SN - 1532-0456

IS - 4

ER -