Skin microvascular reactivity in trained adolescents

Denise M. Roche, T.W. Rowland, M. Garrard, S. Marwood, V.B. Unnithan

Research output: Contribution to journalArticle

Abstract

Whilst endothelial dysfunction is associated with a sedentary lifestyle, enhanced endothelial function has been documented in the skin of trained individuals. The purpose of this study was to investigate whether highly trained adolescent males possess enhanced skin microvascular endothelial function compared to their untrained peers. Seventeen highly and predominantly soccer trained boys ( V˙O2peakV˙O2peak : 55 ± 6 mL kg−1 min−1) and nine age- and maturation-matched untrained controls ( V˙O2peakV˙O2peak : 43 ± 5 mL kg−1 min−1) aged 13–15 years had skin microvascular endothelial function assessed using laser Doppler flowmetry. Baseline and maximal thermally stimulated skin blood flow (SkBF) responses were higher in forearms of trained subjects compared to untrained participants [baseline SkBF: 11 ± 4 vs. 9 ± 3 perfusion units (PU), p < 0.05; SkBFmax: 282 ± 120 vs. 204 ± 68 PU, p < 0.05]. Similarly, cutaneous vascular conductance (CVC) during local heating was superior in the forearm skin of trained versus untrained individuals (CVCmax: 3 ± 1 vs. 2 ± 1 PU mmHg−1, p < 0.05). Peak hyperaemia following arterial occlusion and area under the reactive hyperaemia curve were also greater in forearm skin of the trained group (peak hyperaemia: 51 ± 21 vs. 35 ± 15 PU, p < 0.05; area under curve: 1596 ± 739 vs. 962 ± 796 PUs, p < 0.05). These results suggest that chronic exercise training in adolescents is associated with enhanced microvascular endothelial vasodilation in non-glabrous skin.
Original languageEnglish
Pages (from-to)1201-1208
Number of pages8
JournalEuropean Journal of Applied Physiology
Volume108
Issue number6
DOIs
Publication statusPublished - 23 Dec 2009

Fingerprint

Skin
Hyperemia
Perfusion
Forearm
Sedentary Lifestyle
Laser-Doppler Flowmetry
Soccer
Vasodilation
Heating
Area Under Curve
Blood Vessels
Exercise

Keywords

  • endothelium
  • post-occlusive reactive hyperaemia
  • cutaneous vascular conductance
  • skin blood flow
  • exercise training
  • adolescents

Cite this

Roche, Denise M. ; Rowland, T.W. ; Garrard, M. ; Marwood, S. ; Unnithan, V.B. / Skin microvascular reactivity in trained adolescents. In: European Journal of Applied Physiology. 2009 ; Vol. 108, No. 6. pp. 1201-1208.
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Skin microvascular reactivity in trained adolescents. / Roche, Denise M.; Rowland, T.W.; Garrard, M.; Marwood, S.; Unnithan, V.B.

In: European Journal of Applied Physiology, Vol. 108, No. 6, 23.12.2009, p. 1201-1208.

Research output: Contribution to journalArticle

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T1 - Skin microvascular reactivity in trained adolescents

AU - Roche, Denise M.

AU - Rowland, T.W.

AU - Garrard, M.

AU - Marwood, S.

AU - Unnithan, V.B.

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N2 - Whilst endothelial dysfunction is associated with a sedentary lifestyle, enhanced endothelial function has been documented in the skin of trained individuals. The purpose of this study was to investigate whether highly trained adolescent males possess enhanced skin microvascular endothelial function compared to their untrained peers. Seventeen highly and predominantly soccer trained boys ( V˙O2peakV˙O2peak : 55 ± 6 mL kg−1 min−1) and nine age- and maturation-matched untrained controls ( V˙O2peakV˙O2peak : 43 ± 5 mL kg−1 min−1) aged 13–15 years had skin microvascular endothelial function assessed using laser Doppler flowmetry. Baseline and maximal thermally stimulated skin blood flow (SkBF) responses were higher in forearms of trained subjects compared to untrained participants [baseline SkBF: 11 ± 4 vs. 9 ± 3 perfusion units (PU), p < 0.05; SkBFmax: 282 ± 120 vs. 204 ± 68 PU, p < 0.05]. Similarly, cutaneous vascular conductance (CVC) during local heating was superior in the forearm skin of trained versus untrained individuals (CVCmax: 3 ± 1 vs. 2 ± 1 PU mmHg−1, p < 0.05). Peak hyperaemia following arterial occlusion and area under the reactive hyperaemia curve were also greater in forearm skin of the trained group (peak hyperaemia: 51 ± 21 vs. 35 ± 15 PU, p < 0.05; area under curve: 1596 ± 739 vs. 962 ± 796 PUs, p < 0.05). These results suggest that chronic exercise training in adolescents is associated with enhanced microvascular endothelial vasodilation in non-glabrous skin.

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KW - post-occlusive reactive hyperaemia

KW - cutaneous vascular conductance

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KW - exercise training

KW - adolescents

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