Short and longer-term effects of tailored pulmonary rehabilitation for difficult-to-control asthma associated with elevated body mass index

C. Ricketts; F. Steffensen; D. S. Buchan; R. Chaudhuri; D. C. Cowan

doi:10.1183/13993003.congress-2022.579

Short and longer-term effects of tailored pulmonary rehabilitation for difficult-to-control asthma associated with elevated body mass index

C. Ricketts^*
, F. Steffensen
, D. S. Buchan
, R. Chaudhuri
, D. C. Cowan

^*Corresponding author for this work

Research output: Contribution to journal › Meeting Abstract › peer-review

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Abstract

Introduction and aims:
Asthma associated with elevated body mass index (BMI) is challenging, with limited treatment options. Benefits of pulmonary rehabilitation (PR) in this population are unclear, but our previous randomised controlled trial (NCT03630432) showed some improved outcomes at 8 weeks. In the current study, we aimed to evaluate short- and longer-term effects of tailored PR in participants with difficult-to-control asthma and BMI ≥25 kg/m2.

Methods:
In this prospective observational study, participants with difficult-to-control asthma and elevated BMI who completed an 8-week asthma-tailored PR course were assessed at 8 (V2) and 52 weeks (V3), and asthma-related outcomes compared to those at baseline (V1), using repeated measures ANOVA.

Results:
96 participants were consented, and 56 entered the study. Significant differences were seen for asthma control questionnaire (ACQ6) (mean (95% CI) at V1 2.5 (2.1-2.9), V2 2.2 (1.8-2.5) and V3 2.3 (1.9-2.7), p

Conclusions:
PR can improve asthma control and reduce exacerbation rates in this population

Original language	English
Article number	579
Journal	European Respiratory Journal
Volume	60
Issue number	Supplement 66
DOIs	https://doi.org/10.1183/13993003.congress-2022.579
Publication status	Published - 1 Dec 2022

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2022 06 15 Ricketts et al Pulmonary acceptedAccepted author manuscript, 125 KB

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title = "Short and longer-term effects of tailored pulmonary rehabilitation for difficult-to-control asthma associated with elevated body mass index",

abstract = "Introduction and aims: Asthma associated with elevated body mass index (BMI) is challenging, with limited treatment options. Benefits of pulmonary rehabilitation (PR) in this population are unclear, but our previous randomised controlled trial (NCT03630432) showed some improved outcomes at 8 weeks. In the current study, we aimed to evaluate short- and longer-term effects of tailored PR in participants with difficult-to-control asthma and BMI ≥25 kg/m2. Methods: In this prospective observational study, participants with difficult-to-control asthma and elevated BMI who completed an 8-week asthma-tailored PR course were assessed at 8 (V2) and 52 weeks (V3), and asthma-related outcomes compared to those at baseline (V1), using repeated measures ANOVA. Results: 96 participants were consented, and 56 entered the study. Significant differences were seen for asthma control questionnaire (ACQ6) (mean (95\% CI) at V1 2.5 (2.1-2.9), V2 2.2 (1.8-2.5) and V3 2.3 (1.9-2.7), p Conclusions: PR can improve asthma control and reduce exacerbation rates in this population",

author = "C. Ricketts and F. Steffensen and Buchan, \{D. S.\} and R. Chaudhuri and Cowan, \{D. C.\}",

year = "2022",

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doi = "10.1183/13993003.congress-2022.579",

language = "English",

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journal = "European Respiratory Journal",

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T1 - Short and longer-term effects of tailored pulmonary rehabilitation for difficult-to-control asthma associated with elevated body mass index

AU - Ricketts, C.

AU - Steffensen, F.

AU - Buchan, D. S.

AU - Chaudhuri, R.

AU - Cowan, D. C.

PY - 2022/12/1

Y1 - 2022/12/1

N2 - Introduction and aims: Asthma associated with elevated body mass index (BMI) is challenging, with limited treatment options. Benefits of pulmonary rehabilitation (PR) in this population are unclear, but our previous randomised controlled trial (NCT03630432) showed some improved outcomes at 8 weeks. In the current study, we aimed to evaluate short- and longer-term effects of tailored PR in participants with difficult-to-control asthma and BMI ≥25 kg/m2. Methods: In this prospective observational study, participants with difficult-to-control asthma and elevated BMI who completed an 8-week asthma-tailored PR course were assessed at 8 (V2) and 52 weeks (V3), and asthma-related outcomes compared to those at baseline (V1), using repeated measures ANOVA. Results: 96 participants were consented, and 56 entered the study. Significant differences were seen for asthma control questionnaire (ACQ6) (mean (95% CI) at V1 2.5 (2.1-2.9), V2 2.2 (1.8-2.5) and V3 2.3 (1.9-2.7), p Conclusions: PR can improve asthma control and reduce exacerbation rates in this population

AB - Introduction and aims: Asthma associated with elevated body mass index (BMI) is challenging, with limited treatment options. Benefits of pulmonary rehabilitation (PR) in this population are unclear, but our previous randomised controlled trial (NCT03630432) showed some improved outcomes at 8 weeks. In the current study, we aimed to evaluate short- and longer-term effects of tailored PR in participants with difficult-to-control asthma and BMI ≥25 kg/m2. Methods: In this prospective observational study, participants with difficult-to-control asthma and elevated BMI who completed an 8-week asthma-tailored PR course were assessed at 8 (V2) and 52 weeks (V3), and asthma-related outcomes compared to those at baseline (V1), using repeated measures ANOVA. Results: 96 participants were consented, and 56 entered the study. Significant differences were seen for asthma control questionnaire (ACQ6) (mean (95% CI) at V1 2.5 (2.1-2.9), V2 2.2 (1.8-2.5) and V3 2.3 (1.9-2.7), p Conclusions: PR can improve asthma control and reduce exacerbation rates in this population

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DO - 10.1183/13993003.congress-2022.579

M3 - Meeting Abstract

SN - 0903-1936

VL - 60

JO - European Respiratory Journal

JF - European Respiratory Journal

IS - Supplement 66

M1 - 579

ER -

Short and longer-term effects of tailored pulmonary rehabilitation for difficult-to-control asthma associated with elevated body mass index

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