Short and longer-term effects of tailored pulmonary rehabilitation for difficult-to-control asthma associated with elevated body mass index

C. Ricketts*, F. Steffensen, D. S. Buchan, R. Chaudhuri, D. C. Cowan

*Corresponding author for this work

Research output: Contribution to journalMeeting Abstractpeer-review

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Abstract

Introduction and aims:
Asthma associated with elevated body mass index (BMI) is challenging, with limited treatment options. Benefits of pulmonary rehabilitation (PR) in this population are unclear, but our previous randomised controlled trial (NCT03630432) showed some improved outcomes at 8 weeks. In the current study, we aimed to evaluate short- and longer-term effects of tailored PR in participants with difficult-to-control asthma and BMI ≥25 kg/m2.

Methods:
In this prospective observational study, participants with difficult-to-control asthma and elevated BMI who completed an 8-week asthma-tailored PR course were assessed at 8 (V2) and 52 weeks (V3), and asthma-related outcomes compared to those at baseline (V1), using repeated measures ANOVA.

Results:
96 participants were consented, and 56 entered the study. Significant differences were seen for asthma control questionnaire (ACQ6) (mean (95% CI) at V1 2.5 (2.1-2.9), V2 2.2 (1.8-2.5) and V3 2.3 (1.9-2.7), p

Conclusions:
PR can improve asthma control and reduce exacerbation rates in this population
Original languageEnglish
Article number579
JournalEuropean Respiratory Journal
Volume60
Issue numberSupplement 66
DOIs
Publication statusPublished - 1 Dec 2022

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