Abstract
Introduction and aims:
Asthma associated with elevated body mass index (BMI) is challenging, with limited treatment options. Benefits of pulmonary rehabilitation (PR) in this population are unclear, but our previous randomised controlled trial (NCT03630432) showed some improved outcomes at 8 weeks. In the current study, we aimed to evaluate short- and longer-term effects of tailored PR in participants with difficult-to-control asthma and BMI ≥25 kg/m2.
Methods:
In this prospective observational study, participants with difficult-to-control asthma and elevated BMI who completed an 8-week asthma-tailored PR course were assessed at 8 (V2) and 52 weeks (V3), and asthma-related outcomes compared to those at baseline (V1), using repeated measures ANOVA.
Results:
96 participants were consented, and 56 entered the study. Significant differences were seen for asthma control questionnaire (ACQ6) (mean (95% CI) at V1 2.5 (2.1-2.9), V2 2.2 (1.8-2.5) and V3 2.3 (1.9-2.7), p
Conclusions:
PR can improve asthma control and reduce exacerbation rates in this population
Asthma associated with elevated body mass index (BMI) is challenging, with limited treatment options. Benefits of pulmonary rehabilitation (PR) in this population are unclear, but our previous randomised controlled trial (NCT03630432) showed some improved outcomes at 8 weeks. In the current study, we aimed to evaluate short- and longer-term effects of tailored PR in participants with difficult-to-control asthma and BMI ≥25 kg/m2.
Methods:
In this prospective observational study, participants with difficult-to-control asthma and elevated BMI who completed an 8-week asthma-tailored PR course were assessed at 8 (V2) and 52 weeks (V3), and asthma-related outcomes compared to those at baseline (V1), using repeated measures ANOVA.
Results:
96 participants were consented, and 56 entered the study. Significant differences were seen for asthma control questionnaire (ACQ6) (mean (95% CI) at V1 2.5 (2.1-2.9), V2 2.2 (1.8-2.5) and V3 2.3 (1.9-2.7), p
Conclusions:
PR can improve asthma control and reduce exacerbation rates in this population
Original language | English |
---|---|
Article number | 579 |
Journal | European Respiratory Journal |
Volume | 60 |
Issue number | Supplement 66 |
DOIs | |
Publication status | Published - 1 Dec 2022 |