Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

D. McKeown; C. J. McHugh; A. McCabe; W.E.  Smith; D. Graham

Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

D. McKeown, C. J. McHugh, A. McCabe, W.E. Smith, D. Graham

Research output: Contribution to journal › Article › peer-review

Abstract

The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.

Original language	English
Pages (from-to)	1227-1230
Number of pages	4
Journal	Heterocycles
Volume	57
Issue number	7
Publication status	Published - 2002
Externally published	Yes

Keywords

Benzotriazole
Chemistry
Organic
Organic Chemistry
Analytical Chemistry
Pharmacology

Cite this

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title = "Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine",

abstract = "The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.",

keywords = "Benzotriazole, Chemistry, Organic, Organic Chemistry, Analytical Chemistry, Pharmacology",

author = "D. McKeown and McHugh, \{C. J.\} and A. McCabe and W.E. Smith and D. Graham",

year = "2002",

language = "English",

volume = "57",

pages = "1227--1230",

journal = "Heterocycles",

publisher = "Japan Institute of Heterocyclic Chemistry",

number = "7",

}

TY - JOUR

T1 - Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

AU - McKeown, D.

AU - McHugh, C. J.

AU - McCabe, A.

AU - Smith, W.E.

AU - Graham, D.

PY - 2002

Y1 - 2002

N2 - The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.

AB - The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.

KW - Benzotriazole

KW - Chemistry

KW - Organic

KW - Organic Chemistry

KW - Analytical Chemistry

KW - Pharmacology

M3 - Article

VL - 57

SP - 1227

EP - 1230

JO - Heterocycles

JF - Heterocycles

IS - 7

ER -

Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

Abstract

Keywords

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