Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

D. McKeown, C. J. McHugh, A. McCabe, W.E. Smith, D. Graham

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2 Citations (Scopus)

Abstract

The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.
Original languageEnglish
Pages (from-to)1227-1230
Number of pages4
JournalHeterocycles
Volume57
Issue number7
Publication statusPublished - 2002
Externally publishedYes

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Keywords

  • Benzotriazole
  • Chemistry
  • Organic
  • Organic Chemistry
  • Analytical Chemistry
  • Pharmacology

Cite this

McKeown, D., McHugh, C. J., McCabe, A., Smith, W. E., & Graham, D. (2002). Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine. Heterocycles, 57(7), 1227-1230.