Recombinant human growth hormone (rhGH): effects on anthropometric, exercise and psychological profiles

Michael R. Graham, Julien S. Baker, Andrew Kicman, David Cowan, Bruce Davies

Research output: Contribution to journalMeeting Abstract

Abstract

This study was designed to investigate the short term effects (6 days) of recombinant human (rh) growth hormone (GH) administration (0.056 mg/kg/day) combined with weight training on body composition, exercise and psychological profile and compare it with weight training alone. Previous work has shown an improvement in these parameters in GH deficient individuals (Cuneo et al. 1991a, b), but not trained athletes (Crist, 1988; Irving, 2004). The subjects who took part in this study, were twenty-four self-prescribing weight lifters (rhGH), aged between 20 and 48 years, and the results were compared with twenty-four non-drug-using age-matched exercise controls (EC). The dosages were administered under the supervision of the authors in the morning, before any training sessions and an administration diary was recorded. Group differences were analysed using a two-way (group x time) repeated measures ANOVA. Between-group differences were analysed using an independent t test. Within-group differences were analysed using a paired t test followed by a post-hoc Bonferroni test. Data for psychological profiles were analysed using a non-parametric-related samples t test. Between-group differences were analysed using a Kruskal-Wallis test. Body fat (%) diminished within the rhGH group (19.1

Where applicable, experiments conform with Society ethical requirements
Original languageEnglish
Article numberPC31
Pages (from-to)29-29
Number of pages1
JournalProceedings of the Physiological Society
Volume1
Publication statusPublished - 19 Dec 2005
Externally publishedYes
EventFocused Meeting: The Neuroscience of Human Movement in Health and Disease - University College London, London, United Kingdom
Duration: 19 Dec 200520 Dec 2005

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Human Growth Hormone
Growth Hormone
Exercise
Psychology
Weights and Measures
Body Composition
Athletes
Adipose Tissue
Analysis of Variance

Cite this

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title = "Recombinant human growth hormone (rhGH): effects on anthropometric, exercise and psychological profiles",
abstract = "This study was designed to investigate the short term effects (6 days) of recombinant human (rh) growth hormone (GH) administration (0.056 mg/kg/day) combined with weight training on body composition, exercise and psychological profile and compare it with weight training alone. Previous work has shown an improvement in these parameters in GH deficient individuals (Cuneo et al. 1991a, b), but not trained athletes (Crist, 1988; Irving, 2004). The subjects who took part in this study, were twenty-four self-prescribing weight lifters (rhGH), aged between 20 and 48 years, and the results were compared with twenty-four non-drug-using age-matched exercise controls (EC). The dosages were administered under the supervision of the authors in the morning, before any training sessions and an administration diary was recorded. Group differences were analysed using a two-way (group x time) repeated measures ANOVA. Between-group differences were analysed using an independent t test. Within-group differences were analysed using a paired t test followed by a post-hoc Bonferroni test. Data for psychological profiles were analysed using a non-parametric-related samples t test. Between-group differences were analysed using a Kruskal-Wallis test. Body fat ({\%}) diminished within the rhGH group (19.1Where applicable, experiments conform with Society ethical requirements",
author = "Graham, {Michael R.} and Baker, {Julien S.} and Andrew Kicman and David Cowan and Bruce Davies",
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Recombinant human growth hormone (rhGH) : effects on anthropometric, exercise and psychological profiles. / Graham, Michael R.; Baker, Julien S.; Kicman, Andrew; Cowan, David; Davies, Bruce.

In: Proceedings of the Physiological Society, Vol. 1, PC31, 19.12.2005, p. 29-29.

Research output: Contribution to journalMeeting Abstract

TY - JOUR

T1 - Recombinant human growth hormone (rhGH)

T2 - effects on anthropometric, exercise and psychological profiles

AU - Graham, Michael R.

AU - Baker, Julien S.

AU - Kicman, Andrew

AU - Cowan, David

AU - Davies, Bruce

PY - 2005/12/19

Y1 - 2005/12/19

N2 - This study was designed to investigate the short term effects (6 days) of recombinant human (rh) growth hormone (GH) administration (0.056 mg/kg/day) combined with weight training on body composition, exercise and psychological profile and compare it with weight training alone. Previous work has shown an improvement in these parameters in GH deficient individuals (Cuneo et al. 1991a, b), but not trained athletes (Crist, 1988; Irving, 2004). The subjects who took part in this study, were twenty-four self-prescribing weight lifters (rhGH), aged between 20 and 48 years, and the results were compared with twenty-four non-drug-using age-matched exercise controls (EC). The dosages were administered under the supervision of the authors in the morning, before any training sessions and an administration diary was recorded. Group differences were analysed using a two-way (group x time) repeated measures ANOVA. Between-group differences were analysed using an independent t test. Within-group differences were analysed using a paired t test followed by a post-hoc Bonferroni test. Data for psychological profiles were analysed using a non-parametric-related samples t test. Between-group differences were analysed using a Kruskal-Wallis test. Body fat (%) diminished within the rhGH group (19.1Where applicable, experiments conform with Society ethical requirements

AB - This study was designed to investigate the short term effects (6 days) of recombinant human (rh) growth hormone (GH) administration (0.056 mg/kg/day) combined with weight training on body composition, exercise and psychological profile and compare it with weight training alone. Previous work has shown an improvement in these parameters in GH deficient individuals (Cuneo et al. 1991a, b), but not trained athletes (Crist, 1988; Irving, 2004). The subjects who took part in this study, were twenty-four self-prescribing weight lifters (rhGH), aged between 20 and 48 years, and the results were compared with twenty-four non-drug-using age-matched exercise controls (EC). The dosages were administered under the supervision of the authors in the morning, before any training sessions and an administration diary was recorded. Group differences were analysed using a two-way (group x time) repeated measures ANOVA. Between-group differences were analysed using an independent t test. Within-group differences were analysed using a paired t test followed by a post-hoc Bonferroni test. Data for psychological profiles were analysed using a non-parametric-related samples t test. Between-group differences were analysed using a Kruskal-Wallis test. Body fat (%) diminished within the rhGH group (19.1Where applicable, experiments conform with Society ethical requirements

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