Randomized controlled trial of Accelerated Resolution Therapy (ART) for symptoms of combat-related Post-Traumatic Stress Disorder (PTSD)

Kevin E. Kip, Laney Rosenzweig, Diego F. Hernandez, Amy Shuman, Kelly L. Sullivan, Christopher J. Long, James Taylor, Stephen McGhee, Sue Ann Girling, Trudy Wittenberg, Frances M. Sahebzamani, Cecile A. Lengacher, Rajendra Kadel, David M. Diamond

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

OBJECTIVES: Therapies for post-traumatic stress disorder (PTSD) endorsed by the Department of Defense and Veterans Administration are relatively lengthy, costly, and yield variable success. We evaluated Accelerated Resolution Therapy (ART) for the treatment of combat-related psychological trauma.

METHODS: A randomized controlled trial of ART versus an Attention Control (AC) regimen was conducted among 57 U.S. service members/veterans. After random assignment, those assigned to AC were offered crossover to ART, with 3-month follow-up on all participants. Self-report symptoms of PTSD and comorbidities were analyzed among study completers and by the intention-to-treat principle.

RESULTS: Mean age was 41 ± 13 years with 19% female, 54% Army, and 68% with prior PTSD treatment. The ART was delivered in 3.7 ± 1.1 sessions with a 94% completion rate. Mean reductions in symptoms of PTSD, depression, anxiety, and trauma-related guilt were significantly greater (p < 0.001) with ART compared to AC. Favorable results for those treated with ART persisted at 3 months, including reduction in aggression (p < 0.0001). Adverse treatment-related events were rare and not serious.

CONCLUSIONS: ART appears to be a safe and effective treatment for symptoms of combat-related PTSD, including refractory PTSD, and is delivered in significantly less time than therapies endorsed by the Department of Defense and Veterans Administration.

Original languageEnglish
Pages (from-to)1298-1309
Number of pages12
JournalMilitary medicine
Volume178
Issue number12
DOIs
Publication statusPublished - Dec 2013
Externally publishedYes

Fingerprint

Post-Traumatic Stress Disorders
Randomized Controlled Trials
Therapeutics
United States Department of Veterans Affairs
Guilt
Veterans
Aggression
Self Report
Comorbidity
Anxiety
Depression

Keywords

  • Adult
  • Female
  • Humans
  • Imagery (Psychotherapy)
  • Male
  • Middle Aged
  • Military Personnel
  • Stress Disorders, Post-Traumatic
  • Time Factors
  • Veterans
  • Warfare

Cite this

Kip, K. E., Rosenzweig, L., Hernandez, D. F., Shuman, A., Sullivan, K. L., Long, C. J., ... Diamond, D. M. (2013). Randomized controlled trial of Accelerated Resolution Therapy (ART) for symptoms of combat-related Post-Traumatic Stress Disorder (PTSD). Military medicine, 178(12), 1298-1309. https://doi.org/10.7205/MILMED-D-13-00298
Kip, Kevin E. ; Rosenzweig, Laney ; Hernandez, Diego F. ; Shuman, Amy ; Sullivan, Kelly L. ; Long, Christopher J. ; Taylor, James ; McGhee, Stephen ; Girling, Sue Ann ; Wittenberg, Trudy ; Sahebzamani, Frances M. ; Lengacher, Cecile A. ; Kadel, Rajendra ; Diamond, David M. / Randomized controlled trial of Accelerated Resolution Therapy (ART) for symptoms of combat-related Post-Traumatic Stress Disorder (PTSD). In: Military medicine. 2013 ; Vol. 178, No. 12. pp. 1298-1309.
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abstract = "OBJECTIVES: Therapies for post-traumatic stress disorder (PTSD) endorsed by the Department of Defense and Veterans Administration are relatively lengthy, costly, and yield variable success. We evaluated Accelerated Resolution Therapy (ART) for the treatment of combat-related psychological trauma.METHODS: A randomized controlled trial of ART versus an Attention Control (AC) regimen was conducted among 57 U.S. service members/veterans. After random assignment, those assigned to AC were offered crossover to ART, with 3-month follow-up on all participants. Self-report symptoms of PTSD and comorbidities were analyzed among study completers and by the intention-to-treat principle.RESULTS: Mean age was 41 ± 13 years with 19{\%} female, 54{\%} Army, and 68{\%} with prior PTSD treatment. The ART was delivered in 3.7 ± 1.1 sessions with a 94{\%} completion rate. Mean reductions in symptoms of PTSD, depression, anxiety, and trauma-related guilt were significantly greater (p < 0.001) with ART compared to AC. Favorable results for those treated with ART persisted at 3 months, including reduction in aggression (p < 0.0001). Adverse treatment-related events were rare and not serious.CONCLUSIONS: ART appears to be a safe and effective treatment for symptoms of combat-related PTSD, including refractory PTSD, and is delivered in significantly less time than therapies endorsed by the Department of Defense and Veterans Administration.",
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Kip, KE, Rosenzweig, L, Hernandez, DF, Shuman, A, Sullivan, KL, Long, CJ, Taylor, J, McGhee, S, Girling, SA, Wittenberg, T, Sahebzamani, FM, Lengacher, CA, Kadel, R & Diamond, DM 2013, 'Randomized controlled trial of Accelerated Resolution Therapy (ART) for symptoms of combat-related Post-Traumatic Stress Disorder (PTSD)', Military medicine, vol. 178, no. 12, pp. 1298-1309. https://doi.org/10.7205/MILMED-D-13-00298

Randomized controlled trial of Accelerated Resolution Therapy (ART) for symptoms of combat-related Post-Traumatic Stress Disorder (PTSD). / Kip, Kevin E.; Rosenzweig, Laney; Hernandez, Diego F.; Shuman, Amy; Sullivan, Kelly L.; Long, Christopher J.; Taylor, James; McGhee, Stephen; Girling, Sue Ann; Wittenberg, Trudy; Sahebzamani, Frances M.; Lengacher, Cecile A.; Kadel, Rajendra; Diamond, David M.

In: Military medicine, Vol. 178, No. 12, 12.2013, p. 1298-1309.

Research output: Contribution to journalArticle

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T1 - Randomized controlled trial of Accelerated Resolution Therapy (ART) for symptoms of combat-related Post-Traumatic Stress Disorder (PTSD)

AU - Kip, Kevin E.

AU - Rosenzweig, Laney

AU - Hernandez, Diego F.

AU - Shuman, Amy

AU - Sullivan, Kelly L.

AU - Long, Christopher J.

AU - Taylor, James

AU - McGhee, Stephen

AU - Girling, Sue Ann

AU - Wittenberg, Trudy

AU - Sahebzamani, Frances M.

AU - Lengacher, Cecile A.

AU - Kadel, Rajendra

AU - Diamond, David M.

N1 - Reprint & Copyright © 2013 Association of Military Surgeons of the U.S.

PY - 2013/12

Y1 - 2013/12

N2 - OBJECTIVES: Therapies for post-traumatic stress disorder (PTSD) endorsed by the Department of Defense and Veterans Administration are relatively lengthy, costly, and yield variable success. We evaluated Accelerated Resolution Therapy (ART) for the treatment of combat-related psychological trauma.METHODS: A randomized controlled trial of ART versus an Attention Control (AC) regimen was conducted among 57 U.S. service members/veterans. After random assignment, those assigned to AC were offered crossover to ART, with 3-month follow-up on all participants. Self-report symptoms of PTSD and comorbidities were analyzed among study completers and by the intention-to-treat principle.RESULTS: Mean age was 41 ± 13 years with 19% female, 54% Army, and 68% with prior PTSD treatment. The ART was delivered in 3.7 ± 1.1 sessions with a 94% completion rate. Mean reductions in symptoms of PTSD, depression, anxiety, and trauma-related guilt were significantly greater (p < 0.001) with ART compared to AC. Favorable results for those treated with ART persisted at 3 months, including reduction in aggression (p < 0.0001). Adverse treatment-related events were rare and not serious.CONCLUSIONS: ART appears to be a safe and effective treatment for symptoms of combat-related PTSD, including refractory PTSD, and is delivered in significantly less time than therapies endorsed by the Department of Defense and Veterans Administration.

AB - OBJECTIVES: Therapies for post-traumatic stress disorder (PTSD) endorsed by the Department of Defense and Veterans Administration are relatively lengthy, costly, and yield variable success. We evaluated Accelerated Resolution Therapy (ART) for the treatment of combat-related psychological trauma.METHODS: A randomized controlled trial of ART versus an Attention Control (AC) regimen was conducted among 57 U.S. service members/veterans. After random assignment, those assigned to AC were offered crossover to ART, with 3-month follow-up on all participants. Self-report symptoms of PTSD and comorbidities were analyzed among study completers and by the intention-to-treat principle.RESULTS: Mean age was 41 ± 13 years with 19% female, 54% Army, and 68% with prior PTSD treatment. The ART was delivered in 3.7 ± 1.1 sessions with a 94% completion rate. Mean reductions in symptoms of PTSD, depression, anxiety, and trauma-related guilt were significantly greater (p < 0.001) with ART compared to AC. Favorable results for those treated with ART persisted at 3 months, including reduction in aggression (p < 0.0001). Adverse treatment-related events were rare and not serious.CONCLUSIONS: ART appears to be a safe and effective treatment for symptoms of combat-related PTSD, including refractory PTSD, and is delivered in significantly less time than therapies endorsed by the Department of Defense and Veterans Administration.

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KW - Imagery (Psychotherapy)

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KW - Military Personnel

KW - Stress Disorders, Post-Traumatic

KW - Time Factors

KW - Veterans

KW - Warfare

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