Quantitative estimation of parthenolide in Tanacetum parthenium (L.) Schultz-Bip. cultivated in Egypt

Ali M. El-Shamy, Seham S. El-Hawary, Mostafa E. M. Rateb

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Parthenolide, a germacranolide-type sesquiterpene lactone, was estimated in Tanacetum parthenium (L.) cultivated in Egypt by using colorimetric, planar chromatographic, and high-performance liquid chromatographic (HPLC) methods. Parthenolide levels in the open-field herb and aseptically germinated shoots were also compared by using the HPLC method. Parthenolide was produced and estimated for the first time in the callus culture of the plant. In addition, 2 Egyptian market preparations were analyzed for their parthenolide content by using the HPLC method. The relative standard deviations were 0.093, 0.095, and 0.098% (n 5,5,and 7, respectively), and the corresponding recoveries were 98.2, 98.9, and 99.4% for the colorimetric, planar chromatographic, and HPLC determinations, respectively.
Original languageEnglish
Pages (from-to)21-27
Number of pages7
JournalJournal of AOAC International
Volume90
Issue number1
Publication statusPublished - 2007
Externally publishedYes

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