Preoperative bariatric surgery predictors of type 2 diabetes remission

Joshua Fultang, Ugochukwu Chinaka, Jean Rankin, Andisheh Bakhshi, Abdulmajid Ali

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Abstract

Obesity represents a significant proportion of the global public health burden, with the World Health Organization (WHO) estimating more than 600 million people are affected worldwide. Unfortunately, the epidemic of obesity is linked to the increased prevalence of associated metabolic diseases such as type 2 diabetes mellitus (T2DM). Bariatric surgery as an intervention has been shown to provide sustainable weight loss, and also leads to superior short- and longterm metabolic benefits including T2DM remission. Despite this added advantage conferred by bariatric surgery, emerging evidence has shown that not all patients with T2DM achieve remission postoperatively. As such, to improve patient selection and optimize preoperative counselling, research has focused on the preoperative predictors of T2DM remission following bariatric surgery. Herein, we provide a critical review of the current literature addressing preoperative predictors of T2DM remission and highlight the current gaps in the literature. The review comprised a multistage advanced electronic search of the Ovid/Medline, Embase, and Cochrane online libraries to identify available studies published over the last decade.
Original languageEnglish
Pages (from-to)104-114
Number of pages11
JournalJournal of Obesity & Metabolic Syndrome
Volume30
Issue number2
Early online date13 Jan 2021
DOIs
Publication statusPublished - 30 Jun 2021

Keywords

  • predictor
  • metabolic surgery
  • bariatric surgery
  • remission
  • type 2 diabetes mellitus

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