Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process

Mark Ross; Hannah Lithgow; Lawrence Hayes; Geraint Florida-James

doi:10.1007/978-981-13-3681-2_12

Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process

Mark Ross^*
, Hannah Lithgow
, Lawrence Hayes
, Geraint Florida-James

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter

7 Citations (Scopus)

8 Downloads (Pure)

Abstract

Exercise in young adults has been consistently shown to improve various aspects of physiological and psychological health but we are now realising the potential benefits of exercise with advancing age. Specifically, exercise improves cardiovascular, musculoskeletal, and metabolic health through reductions in oxidative stress, chronic low-grade inflammation and modulating cellular processes within a variety of tissues. In this this chapter we will discuss the effects of acute and chronic exercise on these processes and conditions in an ageing population, and how physical activity affects our vasculature, skeletal muscle function, our immune system, and cardiometabolic risk in older adults.

Original language	English
Title of host publication	Biochemistry and Cell Biology of Ageing
Subtitle of host publication	Part II Clinical Science
Editors	J. Robin Harris, Viktor I. Korolchuk
Place of Publication	Singapore
Publisher	Springer Nature Singapore Pte Ltd
Pages	311-338
Number of pages	28
ISBN (Electronic)	9789811336812
ISBN (Print)	9789811336805
DOIs	https://doi.org/10.1007/978-981-13-3681-2_12
Publication status	E-pub ahead of print - 20 Mar 2019
Externally published	Yes

Publication series

Name	Subcellular Biochemistry
Volume	91
ISSN (Print)	0306-0225

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Ageing
Atrophy
Bone health
Cardiovascular disease
Endothelial function
Exercise
Immunology
Insulin resistance
Oxidative stress
Physical activity
Sarcopenia
Skeletal muscle
Tissue regeneration

Access to Document

10.1007/978-981-13-3681-2_12

2019 01 01 Ross et al Cellular acceptedAccepted author manuscript, 394 KB

http://insight.cumbria.ac.uk/id/eprint/4569/Licence: CC BY-NC

Cite this

Ross, M., Lithgow, H., Hayes, L., & Florida-James, G. (2019). Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process. In J. R. Harris, & V. I. Korolchuk (Eds.), Biochemistry and Cell Biology of Ageing: Part II Clinical Science (pp. 311-338). (Subcellular Biochemistry; Vol. 91). Springer Nature Singapore Pte Ltd. Advance online publication. https://doi.org/10.1007/978-981-13-3681-2_12

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abstract = "Exercise in young adults has been consistently shown to improve various aspects of physiological and psychological health but we are now realising the potential benefits of exercise with advancing age. Specifically, exercise improves cardiovascular, musculoskeletal, and metabolic health through reductions in oxidative stress, chronic low-grade inflammation and modulating cellular processes within a variety of tissues. In this this chapter we will discuss the effects of acute and chronic exercise on these processes and conditions in an ageing population, and how physical activity affects our vasculature, skeletal muscle function, our immune system, and cardiometabolic risk in older adults.",

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Ross, M, Lithgow, H, Hayes, L & Florida-James, G 2019, Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process. in JR Harris & VI Korolchuk (eds), Biochemistry and Cell Biology of Ageing: Part II Clinical Science. Subcellular Biochemistry, vol. 91, Springer Nature Singapore Pte Ltd, Singapore, pp. 311-338. https://doi.org/10.1007/978-981-13-3681-2_12

Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process. / Ross, Mark; Lithgow, Hannah; Hayes, Lawrence et al.
Biochemistry and Cell Biology of Ageing: Part II Clinical Science. ed. / J. Robin Harris; Viktor I. Korolchuk. Singapore: Springer Nature Singapore Pte Ltd, 2019. p. 311-338 (Subcellular Biochemistry; Vol. 91).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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Ross M, Lithgow H, Hayes L, Florida-James G. Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process. In Harris JR, Korolchuk VI, editors, Biochemistry and Cell Biology of Ageing: Part II Clinical Science. Singapore: Springer Nature Singapore Pte Ltd. 2019. p. 311-338. (Subcellular Biochemistry). Epub 2019 Mar 20. doi: 10.1007/978-981-13-3681-2_12