Plasma volume response to 30-s cycle ergometry: influence on lipid and lipoprotein

Christopher J. Retallick, Julien S. Baker, Simon R. Williams, Dean Whitcombe, Bruce Davies

Research output: Contribution to journalArticle

Abstract

PurposeIt has been suggested that exercise-induced changes in plasma volume (PV) confound the interpretation of biochemical data obtained during the recovery period from exercise. No studies have sought to assess the effect of short-duration, high-intensity exercise on PV change and plasma lipid and lipoprotein concentrations. The purpose of this study was to compare power profiles, changes in PV, and plasma lipid and lipoprotein concentrations immediately after and 24 h after exercise.
MethodsSubjects undertook two 30-s, high-intensity cycle ergometer protocols after optimization of resistive loads calculated from total body mass (TBM) and fat-free mass (FFM). Power output indices were recorded and blood samples were analyzed before, immediately after, and 24 h after exercise.
ResultsPeak power outputs were significantly greater in FFM (1020 ± 134 vs 953 ± 114 W for FFM and TBM, respectively, P < 0.05). No differences were found between TBM and FFM for mean power output, fatigue index, or work done. Significant decreases (P < 0.05) in PV of 12.0 ± 5.7 and 12.3 ± 6.7% were recorded immediately after exercise for both TBM and FFM, respectively. At 24 h after exercise, a significant (P < 0.05) increase in PV of 4.2 ± 10.3% was recorded for TBM only. Significant increases (P < 0.01) were recorded for serum triglyceride, cholesterol, HDL cholesterol, and LDL cholesterol immediately after exercise for both TBM and FFM. These increases disappeared when corrected for PV changes, with the exception of LDL cholesterol in TBM, which still displayed a significant increase compared with the preexercise values (2.50 ± 0.74 mM (before) vs 2.72 ± 0.84 mM (immediately after)).
ConclusionsOur data show that short-duration, high-intensity cycle ergometer exercise tests can induce significant plasma volume decreases in untrained subjects, which may affect the interpretation of bloodborne biochemical parameters.
Original languageEnglish
Pages (from-to)1579-1586
Number of pages8
JournalMedicine & Science in Sports & Exercise
Volume39
Issue number9
DOIs
Publication statusPublished - Sep 2007
Externally publishedYes

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Ergometry
Plasma Volume
Lipoproteins
Lipids
Fats
LDL Cholesterol
Exercise Test
HDL Cholesterol
Fatigue
Triglycerides
Cholesterol
Serum

Cite this

Retallick, Christopher J. ; Baker, Julien S. ; Williams, Simon R. ; Whitcombe, Dean ; Davies, Bruce. / Plasma volume response to 30-s cycle ergometry : influence on lipid and lipoprotein. In: Medicine & Science in Sports & Exercise. 2007 ; Vol. 39, No. 9. pp. 1579-1586.
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abstract = "PurposeIt has been suggested that exercise-induced changes in plasma volume (PV) confound the interpretation of biochemical data obtained during the recovery period from exercise. No studies have sought to assess the effect of short-duration, high-intensity exercise on PV change and plasma lipid and lipoprotein concentrations. The purpose of this study was to compare power profiles, changes in PV, and plasma lipid and lipoprotein concentrations immediately after and 24 h after exercise.MethodsSubjects undertook two 30-s, high-intensity cycle ergometer protocols after optimization of resistive loads calculated from total body mass (TBM) and fat-free mass (FFM). Power output indices were recorded and blood samples were analyzed before, immediately after, and 24 h after exercise.ResultsPeak power outputs were significantly greater in FFM (1020 ± 134 vs 953 ± 114 W for FFM and TBM, respectively, P < 0.05). No differences were found between TBM and FFM for mean power output, fatigue index, or work done. Significant decreases (P < 0.05) in PV of 12.0 ± 5.7 and 12.3 ± 6.7{\%} were recorded immediately after exercise for both TBM and FFM, respectively. At 24 h after exercise, a significant (P < 0.05) increase in PV of 4.2 ± 10.3{\%} was recorded for TBM only. Significant increases (P < 0.01) were recorded for serum triglyceride, cholesterol, HDL cholesterol, and LDL cholesterol immediately after exercise for both TBM and FFM. These increases disappeared when corrected for PV changes, with the exception of LDL cholesterol in TBM, which still displayed a significant increase compared with the preexercise values (2.50 ± 0.74 mM (before) vs 2.72 ± 0.84 mM (immediately after)).ConclusionsOur data show that short-duration, high-intensity cycle ergometer exercise tests can induce significant plasma volume decreases in untrained subjects, which may affect the interpretation of bloodborne biochemical parameters.",
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Plasma volume response to 30-s cycle ergometry : influence on lipid and lipoprotein. / Retallick, Christopher J. ; Baker, Julien S.; Williams, Simon R.; Whitcombe, Dean; Davies, Bruce.

In: Medicine & Science in Sports & Exercise, Vol. 39, No. 9, 09.2007, p. 1579-1586.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Plasma volume response to 30-s cycle ergometry

T2 - influence on lipid and lipoprotein

AU - Retallick, Christopher J.

AU - Baker, Julien S.

AU - Williams, Simon R.

AU - Whitcombe, Dean

AU - Davies, Bruce

PY - 2007/9

Y1 - 2007/9

N2 - PurposeIt has been suggested that exercise-induced changes in plasma volume (PV) confound the interpretation of biochemical data obtained during the recovery period from exercise. No studies have sought to assess the effect of short-duration, high-intensity exercise on PV change and plasma lipid and lipoprotein concentrations. The purpose of this study was to compare power profiles, changes in PV, and plasma lipid and lipoprotein concentrations immediately after and 24 h after exercise.MethodsSubjects undertook two 30-s, high-intensity cycle ergometer protocols after optimization of resistive loads calculated from total body mass (TBM) and fat-free mass (FFM). Power output indices were recorded and blood samples were analyzed before, immediately after, and 24 h after exercise.ResultsPeak power outputs were significantly greater in FFM (1020 ± 134 vs 953 ± 114 W for FFM and TBM, respectively, P < 0.05). No differences were found between TBM and FFM for mean power output, fatigue index, or work done. Significant decreases (P < 0.05) in PV of 12.0 ± 5.7 and 12.3 ± 6.7% were recorded immediately after exercise for both TBM and FFM, respectively. At 24 h after exercise, a significant (P < 0.05) increase in PV of 4.2 ± 10.3% was recorded for TBM only. Significant increases (P < 0.01) were recorded for serum triglyceride, cholesterol, HDL cholesterol, and LDL cholesterol immediately after exercise for both TBM and FFM. These increases disappeared when corrected for PV changes, with the exception of LDL cholesterol in TBM, which still displayed a significant increase compared with the preexercise values (2.50 ± 0.74 mM (before) vs 2.72 ± 0.84 mM (immediately after)).ConclusionsOur data show that short-duration, high-intensity cycle ergometer exercise tests can induce significant plasma volume decreases in untrained subjects, which may affect the interpretation of bloodborne biochemical parameters.

AB - PurposeIt has been suggested that exercise-induced changes in plasma volume (PV) confound the interpretation of biochemical data obtained during the recovery period from exercise. No studies have sought to assess the effect of short-duration, high-intensity exercise on PV change and plasma lipid and lipoprotein concentrations. The purpose of this study was to compare power profiles, changes in PV, and plasma lipid and lipoprotein concentrations immediately after and 24 h after exercise.MethodsSubjects undertook two 30-s, high-intensity cycle ergometer protocols after optimization of resistive loads calculated from total body mass (TBM) and fat-free mass (FFM). Power output indices were recorded and blood samples were analyzed before, immediately after, and 24 h after exercise.ResultsPeak power outputs were significantly greater in FFM (1020 ± 134 vs 953 ± 114 W for FFM and TBM, respectively, P < 0.05). No differences were found between TBM and FFM for mean power output, fatigue index, or work done. Significant decreases (P < 0.05) in PV of 12.0 ± 5.7 and 12.3 ± 6.7% were recorded immediately after exercise for both TBM and FFM, respectively. At 24 h after exercise, a significant (P < 0.05) increase in PV of 4.2 ± 10.3% was recorded for TBM only. Significant increases (P < 0.01) were recorded for serum triglyceride, cholesterol, HDL cholesterol, and LDL cholesterol immediately after exercise for both TBM and FFM. These increases disappeared when corrected for PV changes, with the exception of LDL cholesterol in TBM, which still displayed a significant increase compared with the preexercise values (2.50 ± 0.74 mM (before) vs 2.72 ± 0.84 mM (immediately after)).ConclusionsOur data show that short-duration, high-intensity cycle ergometer exercise tests can induce significant plasma volume decreases in untrained subjects, which may affect the interpretation of bloodborne biochemical parameters.

U2 - 10.1249/mss.0b013e318093f585

DO - 10.1249/mss.0b013e318093f585

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EP - 1586

JO - Medicine & Science in Sports & Exercise

JF - Medicine & Science in Sports & Exercise

SN - 0195-9131

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ER -