Pathology pick up rate in routine preoperative endoscopy and its impact on patients undergoing gastric bypass surgery

Abdulmajid Ali*, Peter Ishak, Chinaka Ugochukwu, Andisheh Bakhshi, Rifat Mohamed, Jean Rankin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Background and Aims: Patients with obesity are known for higher chances of having upper gastrointestinal (UGI) pathology and diseases.
Esophagogastroduodenoscopy (OGD) is considered the investigation of choice to detect and confirm UGI pathology in patient with obesity.
The routine OGD as a preoperative workup remained controversial before gastric bypass surgery. The need for preoperative OGD on patients
undergoing bariatric surgery has been a subject of debate among bariatric surgeons. The study’s aim is to evaluate the impact of routine preoperative
endoscopy on patients underwent gastric bypass surgery laparoscopic Roux‑en‑Y gastric bypass (LRYGB). Patients and Materials: Retrospective
review of prospectively kept patients’ records who underwent LRYGB in our unit from February 2009 to March 2020. Patients were divided
into two groups according to the absence or presence of symptoms before their preoperative OGD: Group A (asymptomatic patients) and
Group B (symptomatic patients). Further data on OGD reports, campylobacter‑like organism test and histology results and changes in the
management plan were collected and analyzed. Calculation of post hoc power and Fisher’s exact test was to investigate the correlation between
OGD indication and its findings. All analyses were conducted at a 5% critical level. Results: A total of 114 patients included in the analysis,
85 (74.56%) were in Group A and 29 in Group B. OGD detected pathology in 34 patients in Group A and 21 in Group B (P = 0.004). Those
included hiatus hernia (HH) (17.65% Group A, 44.83% Group B, P = 0.006); stomach ulcer (7.06% Group A, 3.45% Group B, P = 0.676),
Helicobacter pylori (H. pylori) infection (12.86% Group A, 29.41% Group B). This led to change of management in 22 patients in Group A and
12 in Group B (P = 0.157). Those changes included H. pylori eradication (10.59% Group A, 17.24% Group B, P = 0.153), HH repair (3.53%
Group A, 24.14% Group B, P = 0.002). Conclusions: Preoperative OGD has some significant impact on symptomatic patients. However, this
is debatable among asymptomatic patients; hence, cheaper noninvasive alternatives could replace preoperative OGD.
Original languageEnglish
Pages (from-to)7-13
Number of pages7
JournalLibyan Journal of Medical Sciences
Issue number1
Publication statusPublished - 11 Aug 2022


  • bariatric surgery
  • esophago-gastro-duodenoscopy
  • gastric bypass
  • obesity


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