Pathogenesis of fungal infections in cystic fibrosis

Craig Williams, Ranjith Ranjendran, Gordon Ramage

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

For a long time, the microbiology of cystic fibrosis has been focussed on Pseudomonas aeruginosa and associated Gram-negative pathogens. An increasing body of evidence has been compiled demonstrating an important role for moulds and yeasts within this complex patient group. Whether or not fungi are active participants, spectators or transient passersby remain to be elucidated. However, functionally, they do appear to play a contributory role in pathogenesis, albeit we do not know if this is a direct or indirect effect. The following review examines some of the key evidence for the role of fungi in CF pathogenesis.
Original languageEnglish
Pages (from-to)163-169
Number of pages7
JournalCurrent Fungal Infection Reports
Volume10
Issue number4
Early online date7 Dec 2016
DOIs
Publication statusPublished - Dec 2016

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Keywords

  • fungal infections
  • cystic fibrosis
  • pathogenesis
  • pseudomonas aeruginosa
  • review

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