Ozone application in different industries: a review of recent developments

Emmanuel I. Epelle, Andrew Macfarlane, Michael Cusack, Anthony Burns, Jude A. Okolie, William Mackay, Mostafa Rateb, Mohammed Yaseen*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

59 Citations (Scopus)
143 Downloads (Pure)


Ozone – a powerful antimicrobial agent, has been extensively applied for decontamination purposes in several industries (including food, water treatment, pharmaceuticals, textiles, healthcare, and the medical sectors). The advent of the COVID-19 pandemic has led to recent developments in the deployment of different ozone-based technologies for the decontamination of surfaces, materials and indoor environments. The pandemic has also highlighted the therapeutic potential of ozone for the treatment of COVID-19 patients, with astonishing results observed. The key objective of this review is to summarize recent advances in the utilisation of ozone for decontamination applications in the above-listed industries while emphasising the impact of key parameters affecting microbial reduction efficiency and ozone stability for prolonged action. We realise that aqueous ozonation has received higher research attention, compared to the gaseous application of ozone. This can be attributed to the fact that water treatment represents one of its earliest applications. Furthermore, the application of gaseous ozone for personal protective equipment (PPE) and medical device disinfection has not received a significant number of contributions compared to other applications. This presents a challenge for which the correct application of ozonation can mitigate. In this review, a critical discussion of these challenges is presented, as well as key knowledge gaps and open research problems/opportunities.
Original languageEnglish
Article number140188
Number of pages21
JournalChemical Engineering Journal
Issue numberPart 2
Early online date6 Nov 2022
Publication statusPublished - 15 Feb 2023


  • ozone
  • ozone dosage
  • personal protective equipment (PPE)
  • microbial inactivation
  • decontamination


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