Modulation of catecholamine release and cortisol secretion by social interaction in the rainbow trout, Oncorhynchus mykiss.

Katherine A. Sloman, Colin J. Montpetit, Kathleen M. Gilmour

Research output: Contribution to journalArticle

Abstract

The objective of the present study was to investigate the effect of social status on the ability of rainbow trout to secrete the stress hormones, cortisol, and catecholamines. Rainbow trout were confined in pairs for six days to permit the formation of dominance hierarchies. An in situ saline-perfused posterior cardinal vein (PCV) preparation was then used to assess cortisol secretion or release of the catecholamine hormones, adrenaline and noradrenaline, in response to the inclusion of appropriate secretagogues in the perfusate. Fish identified as subordinate on the basis of their behaviour showed a characteristic elevation of circulating plasma cortisol concentrations when compared with dominant fish. When the interrenal cells were stimulated in situ with adrenocorticotropic hormone, subordinate fish displayed a significantly lower rate of cortisol secretion than dominant fish. However, social status had no significant effect on either adrenaline or noradrenaline secretion rates upon stimulation of the chromaffin cells in situ with acetylcholine. These results suggest that the chronic elevation of plasma cortisol associated with subordinate social status in rainbow trout reduces the sensitivity of the cortisol-secreting interrenal cells, presumably through negative feedback mechanisms.
Original languageEnglish
Pages (from-to)136-146
Number of pages11
JournalGeneral and Comparative Endocrinology
Volume127
Issue number2
DOIs
Publication statusPublished - 2002
Externally publishedYes

Fingerprint

Oncorhynchus mykiss
catecholamines
Interpersonal Relations
Catecholamines
cortisol
Hydrocortisone
secretion
Fishes
epinephrine
norepinephrine
fish
Epinephrine
Norepinephrine
hormones
Hormones
chromaffin cells
Social Dominance
Chromaffin Cells
Aptitude
corticotropin

Keywords

  • Social interactions
  • Stress
  • Cortisol
  • Catecholamines
  • Rainbow trout
  • Oncorhynchus mykiss
  • In situ perfused posterior cardinal vein preparation
  • ACTH
  • Acetylcholine

Cite this

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title = "Modulation of catecholamine release and cortisol secretion by social interaction in the rainbow trout, Oncorhynchus mykiss.",
abstract = "The objective of the present study was to investigate the effect of social status on the ability of rainbow trout to secrete the stress hormones, cortisol, and catecholamines. Rainbow trout were confined in pairs for six days to permit the formation of dominance hierarchies. An in situ saline-perfused posterior cardinal vein (PCV) preparation was then used to assess cortisol secretion or release of the catecholamine hormones, adrenaline and noradrenaline, in response to the inclusion of appropriate secretagogues in the perfusate. Fish identified as subordinate on the basis of their behaviour showed a characteristic elevation of circulating plasma cortisol concentrations when compared with dominant fish. When the interrenal cells were stimulated in situ with adrenocorticotropic hormone, subordinate fish displayed a significantly lower rate of cortisol secretion than dominant fish. However, social status had no significant effect on either adrenaline or noradrenaline secretion rates upon stimulation of the chromaffin cells in situ with acetylcholine. These results suggest that the chronic elevation of plasma cortisol associated with subordinate social status in rainbow trout reduces the sensitivity of the cortisol-secreting interrenal cells, presumably through negative feedback mechanisms.",
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Modulation of catecholamine release and cortisol secretion by social interaction in the rainbow trout, Oncorhynchus mykiss. / Sloman, Katherine A.; Montpetit, Colin J.; Gilmour, Kathleen M.

In: General and Comparative Endocrinology, Vol. 127, No. 2, 2002, p. 136-146.

Research output: Contribution to journalArticle

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AB - The objective of the present study was to investigate the effect of social status on the ability of rainbow trout to secrete the stress hormones, cortisol, and catecholamines. Rainbow trout were confined in pairs for six days to permit the formation of dominance hierarchies. An in situ saline-perfused posterior cardinal vein (PCV) preparation was then used to assess cortisol secretion or release of the catecholamine hormones, adrenaline and noradrenaline, in response to the inclusion of appropriate secretagogues in the perfusate. Fish identified as subordinate on the basis of their behaviour showed a characteristic elevation of circulating plasma cortisol concentrations when compared with dominant fish. When the interrenal cells were stimulated in situ with adrenocorticotropic hormone, subordinate fish displayed a significantly lower rate of cortisol secretion than dominant fish. However, social status had no significant effect on either adrenaline or noradrenaline secretion rates upon stimulation of the chromaffin cells in situ with acetylcholine. These results suggest that the chronic elevation of plasma cortisol associated with subordinate social status in rainbow trout reduces the sensitivity of the cortisol-secreting interrenal cells, presumably through negative feedback mechanisms.

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