Mitigation of ROS insults by streptomyces secondary metabolites in primary cortical neurons

Keyphrases

• Oxidative Stress 100%
• Insults 100%
• Secondary Metabolites 100%
• Streptomyces 100%
• Primary Cortical Neurons 100%
• Neurodegenerative Diseases 66%
• Undecylprodigiosin 66%
• Alzheimer's Disease 33%
• Mitochondria 33%
• Parkinson's Disease 33%
• Mitochondrial Function 33%
• Glutathione 33%
• New Drugs 33%
• Natural Products 33%
• Streptomyces Metabolites 33%
• Mitochondrial Dysfunction 33%
• Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) 33%
• Hydrogen Peroxide 33%
• Complete Protection 33%
• Cytosolic Ca2+ 33%
• In Vitro Model 33%
• Nrf2-ARE Pathway 33%
• Widely-connected 33%
• Cerebral Ischemia 33%
• Caspase-3 Activity 33%
• Pyrrole 33%
• Nuclear Translocation 33%
• Inductors 33%
• Nrf2 Pathway 33%
• ROS Production 33%
• Enzyme Level 33%
• Cellular Targets 33%
• Quinones 33%
• ROS Release 33%
• Neuronal Cytotoxicity 33%
• Catalase 33%
• Staurosporine 33%
• Mitochondrial Uncoupler 33%
• Antioxidant Enzymes 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Streptomyces 100%
• Transcription Factor Nrf2 100%
• Carbonyl Cyanide 4 (Trifluoromethoxy)phenylhydrazone 66%
• Antioxidant 33%
• Alzheimer's Disease 33%
• Glutathione 33%
• Calcium Ion 33%
• Natural Product 33%
• Degenerative Disease 33%
• Hydrogen Peroxide 33%
• Parkinson's Disease 33%
• Brain Ischemia 33%
• Staurosporine 33%
• Catalase 33%
• Caspase 3 33%
• Cytotoxicity 33%
• Pyrrole 33%

Neuroscience

• Photosynthetic Pigment 33%