Micro/nano-patterning of DNA and rapid readout with SERS tags

Shuging Sun, David Thompson, Ute Schmidt, Duncan Graham, Graham J. Leggett

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Hybridisation of oligonucleotide micro- and nano-structures, formed using far- and near-field optical lithography, with Raman dye-labelled silver nanoparticles functionalised with complementary oligonucleotides yields striking contrast, attributed to Raman “hot-spot” formation, and enables rapid, convenient read-out by Raman microscopy.
Original languageEnglish
Pages (from-to)5292-5294
Number of pages3
Issue number29
Publication statusPublished - 2010
Externally publishedYes


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