Left ventricular twist mechanics during incremental cycling and knee extension exercise in healthy men

Alexander Beaumont, John Hough, Nicholas Sculthorpe, Joanna Richards

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Abstract

PurposeThe objective of the present study was to investigate left ventricular (LV) twist mechanics in response to incremental cycling and isometric knee extension exercises.
MethodsTwenty-six healthy male participants (age = 30.42 ± 6.17 years) were used to study peak twist mechanics at rest and during incremental semi-supine cycling at 30 and 60% work rate maximum (Wmax) and during short duration (15 s contractions) isometric knee extension at 40 and 75% maximum voluntary contraction (MVC), using two-dimensional speckle tracking echocardiography.
ResultsData presented as mean ± standard deviation or median (interquartile range). LV twist increased from rest to 30% Wmax (13.21° ± 4.63° to 20.04° ± 4.76°, p < 0.001) then remained unchanged. LV systolic and diastolic twisting velocities progressively increased with exercise intensity during cycling from rest to 60% Wmax (twisting, 88.21° ± 20.51° to 209.05° ± 34.56° s−1, p < 0.0001; untwisting, −93.90 (29.62)° to −267.31 (104.30)° s−1, p < 0.0001). During the knee extension exercise, LV twist remained unchanged with progressive intensity (rest 13.40° ± 4.80° to 75% MVC 16.77° ± 5.54°, p > 0.05), whilst twisting velocity increased (rest 89.15° ± 21.77° s−1 to 75% MVC 124.32° ± 34.89° s−1, p < 0.01). Untwisting velocity remained unchanged from rest [−90.60 (27.19)° s−1] to 40% MVC (p > 0.05) then increased from 40 to 75% MVC [−98.44 (43.54)° s−1 to −138.42 (73.29)° s−1, p < 0.01]. Apical rotations and rotational velocities were greater than basal during all conditions and intensities (all p < 0.01).
ConclusionCycling increased LV twist to 30% Wmax which then remained unchanged thereafter, whereas twisting velocities showed further increases to greater intensities. A novel finding is that LV twist was unaffected by incremental knee extension, yet systolic and diastolic twisting velocities augmented with isometric exercise.
Original languageEnglish
JournalEuropean Journal of Applied Physiology
Early online date4 Dec 2016
DOIs
Publication statusE-pub ahead of print - 4 Dec 2016

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Mechanics
Knee
Exercise
Isometric Contraction
Echocardiography
Healthy Volunteers

Cite this

@article{2b9da00aa7cd4dceadec6a354234cf03,
title = "Left ventricular twist mechanics during incremental cycling and knee extension exercise in healthy men",
abstract = "PurposeThe objective of the present study was to investigate left ventricular (LV) twist mechanics in response to incremental cycling and isometric knee extension exercises.MethodsTwenty-six healthy male participants (age = 30.42 ± 6.17 years) were used to study peak twist mechanics at rest and during incremental semi-supine cycling at 30 and 60{\%} work rate maximum (Wmax) and during short duration (15 s contractions) isometric knee extension at 40 and 75{\%} maximum voluntary contraction (MVC), using two-dimensional speckle tracking echocardiography.ResultsData presented as mean ± standard deviation or median (interquartile range). LV twist increased from rest to 30{\%} Wmax (13.21° ± 4.63° to 20.04° ± 4.76°, p < 0.001) then remained unchanged. LV systolic and diastolic twisting velocities progressively increased with exercise intensity during cycling from rest to 60{\%} Wmax (twisting, 88.21° ± 20.51° to 209.05° ± 34.56° s−1, p < 0.0001; untwisting, −93.90 (29.62)° to −267.31 (104.30)° s−1, p < 0.0001). During the knee extension exercise, LV twist remained unchanged with progressive intensity (rest 13.40° ± 4.80° to 75{\%} MVC 16.77° ± 5.54°, p > 0.05), whilst twisting velocity increased (rest 89.15° ± 21.77° s−1 to 75{\%} MVC 124.32° ± 34.89° s−1, p < 0.01). Untwisting velocity remained unchanged from rest [−90.60 (27.19)° s−1] to 40{\%} MVC (p > 0.05) then increased from 40 to 75{\%} MVC [−98.44 (43.54)° s−1 to −138.42 (73.29)° s−1, p < 0.01]. Apical rotations and rotational velocities were greater than basal during all conditions and intensities (all p < 0.01).ConclusionCycling increased LV twist to 30{\%} Wmax which then remained unchanged thereafter, whereas twisting velocities showed further increases to greater intensities. A novel finding is that LV twist was unaffected by incremental knee extension, yet systolic and diastolic twisting velocities augmented with isometric exercise.",
author = "Alexander Beaumont and John Hough and Nicholas Sculthorpe and Joanna Richards",
year = "2016",
month = "12",
day = "4",
doi = "10.1007/s00421-016-3506-8",
language = "English",
journal = "European Journal of Applied Physiology",
issn = "1439-6319",
publisher = "Springer-Verlag",

}

TY - JOUR

T1 - Left ventricular twist mechanics during incremental cycling and knee extension exercise in healthy men

AU - Beaumont, Alexander

AU - Hough, John

AU - Sculthorpe, Nicholas

AU - Richards, Joanna

PY - 2016/12/4

Y1 - 2016/12/4

N2 - PurposeThe objective of the present study was to investigate left ventricular (LV) twist mechanics in response to incremental cycling and isometric knee extension exercises.MethodsTwenty-six healthy male participants (age = 30.42 ± 6.17 years) were used to study peak twist mechanics at rest and during incremental semi-supine cycling at 30 and 60% work rate maximum (Wmax) and during short duration (15 s contractions) isometric knee extension at 40 and 75% maximum voluntary contraction (MVC), using two-dimensional speckle tracking echocardiography.ResultsData presented as mean ± standard deviation or median (interquartile range). LV twist increased from rest to 30% Wmax (13.21° ± 4.63° to 20.04° ± 4.76°, p < 0.001) then remained unchanged. LV systolic and diastolic twisting velocities progressively increased with exercise intensity during cycling from rest to 60% Wmax (twisting, 88.21° ± 20.51° to 209.05° ± 34.56° s−1, p < 0.0001; untwisting, −93.90 (29.62)° to −267.31 (104.30)° s−1, p < 0.0001). During the knee extension exercise, LV twist remained unchanged with progressive intensity (rest 13.40° ± 4.80° to 75% MVC 16.77° ± 5.54°, p > 0.05), whilst twisting velocity increased (rest 89.15° ± 21.77° s−1 to 75% MVC 124.32° ± 34.89° s−1, p < 0.01). Untwisting velocity remained unchanged from rest [−90.60 (27.19)° s−1] to 40% MVC (p > 0.05) then increased from 40 to 75% MVC [−98.44 (43.54)° s−1 to −138.42 (73.29)° s−1, p < 0.01]. Apical rotations and rotational velocities were greater than basal during all conditions and intensities (all p < 0.01).ConclusionCycling increased LV twist to 30% Wmax which then remained unchanged thereafter, whereas twisting velocities showed further increases to greater intensities. A novel finding is that LV twist was unaffected by incremental knee extension, yet systolic and diastolic twisting velocities augmented with isometric exercise.

AB - PurposeThe objective of the present study was to investigate left ventricular (LV) twist mechanics in response to incremental cycling and isometric knee extension exercises.MethodsTwenty-six healthy male participants (age = 30.42 ± 6.17 years) were used to study peak twist mechanics at rest and during incremental semi-supine cycling at 30 and 60% work rate maximum (Wmax) and during short duration (15 s contractions) isometric knee extension at 40 and 75% maximum voluntary contraction (MVC), using two-dimensional speckle tracking echocardiography.ResultsData presented as mean ± standard deviation or median (interquartile range). LV twist increased from rest to 30% Wmax (13.21° ± 4.63° to 20.04° ± 4.76°, p < 0.001) then remained unchanged. LV systolic and diastolic twisting velocities progressively increased with exercise intensity during cycling from rest to 60% Wmax (twisting, 88.21° ± 20.51° to 209.05° ± 34.56° s−1, p < 0.0001; untwisting, −93.90 (29.62)° to −267.31 (104.30)° s−1, p < 0.0001). During the knee extension exercise, LV twist remained unchanged with progressive intensity (rest 13.40° ± 4.80° to 75% MVC 16.77° ± 5.54°, p > 0.05), whilst twisting velocity increased (rest 89.15° ± 21.77° s−1 to 75% MVC 124.32° ± 34.89° s−1, p < 0.01). Untwisting velocity remained unchanged from rest [−90.60 (27.19)° s−1] to 40% MVC (p > 0.05) then increased from 40 to 75% MVC [−98.44 (43.54)° s−1 to −138.42 (73.29)° s−1, p < 0.01]. Apical rotations and rotational velocities were greater than basal during all conditions and intensities (all p < 0.01).ConclusionCycling increased LV twist to 30% Wmax which then remained unchanged thereafter, whereas twisting velocities showed further increases to greater intensities. A novel finding is that LV twist was unaffected by incremental knee extension, yet systolic and diastolic twisting velocities augmented with isometric exercise.

U2 - 10.1007/s00421-016-3506-8

DO - 10.1007/s00421-016-3506-8

M3 - Article

JO - European Journal of Applied Physiology

JF - European Journal of Applied Physiology

SN - 1439-6319

ER -