Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp

Noor Erma Sugijanto, Arnulf Diesel, Mostafa Rateb, Alexander Pretsch, Selma Gogalic, Noor Cholies Zaini, Rainer Ebel, Gunawan Indrayanto

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)-oxacyclotetracosan-1-one, was isolated from the endophyticfungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5 – 125 g/mL.
Original languageEnglish
Pages (from-to)677-678
Number of pages2
JournalNatutral Product Communications
Volume6
Issue number5
Publication statusPublished - 2011
Externally publishedYes

Keywords

  • Lecythophora sp
  • Alyxia reinwardtii
  • endophytic fungus
  • lecythomycin
  • macrolactone glycoside

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