Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp

Noor Erma Sugijanto; Arnulf Diesel; Mostafa Rateb; Alexander Pretsch; Selma Gogalic; Noor Cholies Zaini; Rainer Ebel; Gunawan Indrayanto

Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp

Noor Erma Sugijanto, Arnulf Diesel, Mostafa Rateb, Alexander Pretsch, Selma Gogalic, Noor Cholies Zaini, Rainer Ebel, Gunawan Indrayanto

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)-oxacyclotetracosan-1-one, was isolated from the endophyticfungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5 – 125 g/mL.

Original language	English
Pages (from-to)	677-678
Number of pages	2
Journal	Natutral Product Communications
Volume	6
Issue number	5
Publication status	Published - 2011
Externally published	Yes

Keywords

Lecythophora sp
Alyxia reinwardtii
endophytic fungus
lecythomycin
macrolactone glycoside

Cite this

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title = "Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp",

abstract = "A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)-oxacyclotetracosan-1-one, was isolated from the endophyticfungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5 – 125 g/mL.",

keywords = "Lecythophora sp, Alyxia reinwardtii, endophytic fungus, lecythomycin, macrolactone glycoside",

author = "Sugijanto, {Noor Erma} and Arnulf Diesel and Mostafa Rateb and Alexander Pretsch and Selma Gogalic and Zaini, {Noor Cholies} and Rainer Ebel and Gunawan Indrayanto",

year = "2011",

language = "English",

volume = "6",

pages = "677--678",

journal = "Natutral Product Communications",

issn = "1555-9475",

publisher = "Natural Product Communications",

number = "5",

}

TY - JOUR

T1 - Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp

AU - Sugijanto, Noor Erma

AU - Diesel, Arnulf

AU - Rateb, Mostafa

AU - Pretsch, Alexander

AU - Gogalic, Selma

AU - Zaini, Noor Cholies

AU - Ebel, Rainer

AU - Indrayanto, Gunawan

PY - 2011

Y1 - 2011

N2 - A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)-oxacyclotetracosan-1-one, was isolated from the endophyticfungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5 – 125 g/mL.

AB - A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)-oxacyclotetracosan-1-one, was isolated from the endophyticfungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5 – 125 g/mL.

KW - Lecythophora sp

KW - Alyxia reinwardtii

KW - endophytic fungus

KW - lecythomycin

KW - macrolactone glycoside

M3 - Article

SN - 1555-9475

VL - 6

SP - 677

EP - 678

JO - Natutral Product Communications

JF - Natutral Product Communications

IS - 5

ER -

Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp

Abstract

Keywords

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