Laser melting of NiTi and its effects  on in vitro mesenchymal stem cell responses

D.G. Waugh; J. Lawrence; C.W. Chan; I. Hussain; H.C. Man

doi:10.1016/B978-1-78242-074-3.00027-1

Laser melting of NiTi and its effects on in vitro mesenchymal stem cell responses

D.G. Waugh, J. Lawrence, C.W. Chan, I. Hussain, H.C. Man

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Citations (Scopus)

Abstract

Control of cell adhesion to synthetic polymers is a key factor in tissue engineering. The bioactivity of NiTi after laser melting was investigated implementing in vitro techniques for studying mesenchymal stem cell (MSC) responses. The effects of physical (surface roughness and topography) and chemical (surface Ti/Ni ratio) modifications as a consequence of laser melting on the cell morphology and cell coverage were studied. The results indicate that MSC morphology was affected primarily by topographical factors. No toxic effect in terms of Ni release affected the MSCs, as evidenced by the adhesion and spreading of the cells.

Original language	English
Title of host publication	Laser Surface Engineering
Subtitle of host publication	Processes and Applications
Editors	J. Lawrence, D.G. Waugh
Place of Publication	United Kingdom
Publisher	Woodhead Publishing Limited
Chapter	27
Pages	653-676
Number of pages	24
ISBN (Print)	9781782420743
DOIs	https://doi.org/10.1016/B978-1-78242-074-3.00027-1
Publication status	Published - 2015
Externally published	Yes

Publication series

Name	Woodhead Publishing Series in Electronic and Optical Materials
Publisher	Woodhead Publishing

Keywords

fiber laser
laser melting
mesenchymal stem cell (MSC)
NiTi

Access to Document

10.1016/B978-1-78242-074-3.00027-1

Cite this

Waugh, D. G., Lawrence, J., Chan, C. W., Hussain, I., & Man, H. C. (2015). Laser melting of NiTi and its effects on in vitro mesenchymal stem cell responses. In J. Lawrence, & D. G. Waugh (Eds.), Laser Surface Engineering: Processes and Applications (pp. 653-676). (Woodhead Publishing Series in Electronic and Optical Materials). Woodhead Publishing Limited. https://doi.org/10.1016/B978-1-78242-074-3.00027-1

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abstract = "Control of cell adhesion to synthetic polymers is a key factor in tissue engineering. The bioactivity of NiTi after laser melting was investigated implementing in vitro techniques for studying mesenchymal stem cell (MSC) responses. The effects of physical (surface roughness and topography) and chemical (surface Ti/Ni ratio) modifications as a consequence of laser melting on the cell morphology and cell coverage were studied. The results indicate that MSC morphology was affected primarily by topographical factors. No toxic effect in terms of Ni release affected the MSCs, as evidenced by the adhesion and spreading of the cells.",

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author = "D.G. Waugh and J. Lawrence and C.W. Chan and I. Hussain and H.C. Man",

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Waugh, DG, Lawrence, J, Chan, CW, Hussain, I & Man, HC 2015, Laser melting of NiTi and its effects on in vitro mesenchymal stem cell responses. in J Lawrence & DG Waugh (eds), Laser Surface Engineering: Processes and Applications. Woodhead Publishing Series in Electronic and Optical Materials, Woodhead Publishing Limited, United Kingdom, pp. 653-676. https://doi.org/10.1016/B978-1-78242-074-3.00027-1

Laser melting of NiTi and its effects on in vitro mesenchymal stem cell responses. / Waugh, D.G.; Lawrence, J.; Chan, C.W. et al.
Laser Surface Engineering: Processes and Applications. ed. / J. Lawrence; D.G. Waugh. United Kingdom: Woodhead Publishing Limited, 2015. p. 653-676 (Woodhead Publishing Series in Electronic and Optical Materials).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

TY - CHAP

T1 - Laser melting of NiTi and its effects on in vitro mesenchymal stem cell responses

AU - Waugh, D.G.

AU - Lawrence, J.

AU - Chan, C.W.

AU - Hussain, I.

AU - Man, H.C.

PY - 2015

Y1 - 2015

N2 - Control of cell adhesion to synthetic polymers is a key factor in tissue engineering. The bioactivity of NiTi after laser melting was investigated implementing in vitro techniques for studying mesenchymal stem cell (MSC) responses. The effects of physical (surface roughness and topography) and chemical (surface Ti/Ni ratio) modifications as a consequence of laser melting on the cell morphology and cell coverage were studied. The results indicate that MSC morphology was affected primarily by topographical factors. No toxic effect in terms of Ni release affected the MSCs, as evidenced by the adhesion and spreading of the cells.

AB - Control of cell adhesion to synthetic polymers is a key factor in tissue engineering. The bioactivity of NiTi after laser melting was investigated implementing in vitro techniques for studying mesenchymal stem cell (MSC) responses. The effects of physical (surface roughness and topography) and chemical (surface Ti/Ni ratio) modifications as a consequence of laser melting on the cell morphology and cell coverage were studied. The results indicate that MSC morphology was affected primarily by topographical factors. No toxic effect in terms of Ni release affected the MSCs, as evidenced by the adhesion and spreading of the cells.

KW - fiber laser

KW - laser melting

KW - mesenchymal stem cell (MSC)

KW - NiTi

U2 - 10.1016/B978-1-78242-074-3.00027-1

DO - 10.1016/B978-1-78242-074-3.00027-1

M3 - Chapter

SN - 9781782420743

T3 - Woodhead Publishing Series in Electronic and Optical Materials

SP - 653

EP - 676

BT - Laser Surface Engineering

A2 - Lawrence, J.

A2 - Waugh, D.G.

PB - Woodhead Publishing Limited

CY - United Kingdom

ER -