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HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia
Taranjit Singh Rai
, John J Cole
, David M Nelson
, Dina Dikovskaya
, William J Faller
, Maria Grazia Vizioli
, Rachael N Hewitt
, Orchi Anannya
, Tony McBryan
, Indrani Manoharan
, John van Tuyn
, Nicholas Morrice
, Nikolay A Pchelintsev
, Andre Ivanov
, Claire Brock
, Mark E Drotar
, Colin Nixon
, William Clark
, Owen J Sansom
, Kurt I Anderson
Ayala King, Karen Blyth, Peter D Adams
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School of Health and Life Sciences
Research output
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Contribution to journal
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Article
›
peer-review
107
Citations (Scopus)
Overview
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Keyphrases
Senescent Cells
100%
Senescence
100%
Chromatin Landscape
100%
Neoplasia
100%
Chromatin
66%
H4K16ac
66%
Histone H3
50%
Proliferating Cells
33%
DNA Replication
33%
Replication-independent
33%
Tumor Suppression
33%
Histone H4
33%
Cellular Senescence
33%
H3.3
16%
Chaperone
16%
Histone Chaperone
16%
Oncogene
16%
Canonical Histones
16%
Proliferation Arrest
16%
Expressed Genes
16%
RNA Splicing
16%
Core Histones
16%
Tumorigenesis
16%
Variant Histone
16%
Parallel Changes
16%
Biochemistry, Genetics and Molecular Biology
HIRA
100%
Histone
75%
Promoter Region
25%
DNA Synthesis
25%
Carcinogenesis
12%
Alternative Splicing
12%
Histone H4
12%
Oncogene
12%
Cell Proliferation
12%
Messenger RNA
12%