Haemophilus influenzae in acute exacerbations of chronic obstructive pulmonary disease

Alistair Leanord, Craig Williams

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Chronic obstructive pulmonary disease (COPD) is a common progressive respiratory disease that is associated with infective exacerbations that lead to worsening of symptoms. Many organisms are thought to trigger infective exacerbations, but Haemophilus influenzae is the most commonly isolated bacterium. The role of H. influenzae in infective exacerbations remains uncertain, mainly because the organism chronically colonises patients whose clinical condition is stable. H. influenzae may also comprise part of the normal nasopharyngeal flora in man, making the interpretation of positive cultures difficult in some cases.

Original languageEnglish
Pages (from-to)371-5
Number of pages5
JournalInternational journal of antimicrobial agents
Issue number5
Publication statusPublished - May 2002
Externally publishedYes


  • Acute Disease
  • Anti-Bacterial Agents
  • Haemophilus Infections
  • Haemophilus influenzae
  • Humans
  • Pulmonary Disease, Chronic Obstructive
  • Journal Article
  • Review


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