Gracilins: Spongionella-derived promising compounds for Alzheimer disease

Keyphrases

• Alzheimer's Disease 100%
• Gracilin 100%
• ERK Inhibition 33%
• Therapeutic Use 16%
• Antioxidant 16%
• Potential Therapeutics 16%
• Drug Screening 16%
• Neurodegenerative Diseases 16%
• In Vivo Assay 16%
• Oxidative Stress 16%
• Bioactivity 16%
• Drug Target 16%
• Learning Memory 16%
• Behavioral Tests 16%
• In Vitro Assay 16%
• Neuroblastoma 16%
• Tau Phosphorylation 16%
• Metabolism Study 16%
• Alzheimer's Disease Model 16%
• SH-SY5Y Cells 16%
• β-site APP-cleaving Enzyme 1 (BACE1) 16%
• Phosphorylated tau 16%
• Cellular Models 16%
• Tau Levels 16%
• 3xTg-AD 16%
• Neurodegenerative Pathologies 16%
• Mitochondrial Targeting 16%
• Spatial Memory 16%
• Intraperitoneal Injection 16%
• Multi-target Approach 16%
• Nrf2 Translocation 16%
• Mitochondrial Dysfunction 16%
• Positive Trend 16%
• Anti-Alzheimer Drugs 16%
• APP Metabolism 16%
• Tau Hyperphosphorylation 16%
• Diterpenoids 16%
• Multitarget Drugs 16%
• BACE1 Inhibition 16%

Medicine and Dentistry

• Alzheimer's Disease 100%
• Tau 50%
• In Vitro 16%
• Oxidative Stress 16%
• Hyperphosphorylation 16%
• SH-SY5Y 16%
• Spatial Memory 16%
• Cellular Model 16%
• Antioxidant 16%
• Ganglioneuroblastoma 16%
• Transcription Factor Nrf2 16%
• Diterpenoid 16%
• Degenerative Disease 16%
• Drug Screening 16%
• Cell Line 16%
• Amyloid Protein 16%
• Mitochondrial Disorder 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Alzheimer's Disease 100%
• Antioxidant 16%
• Degenerative Disease 16%
• Neuroblastoma 16%
• Drug Screening 16%
• Target Activity 16%
• Transcription Factor Nrf2 16%
• Diterpenoid 16%
• Amyloid Protein 16%