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Gracilins: Spongionella-derived promising compounds for Alzheimer disease
Marta Leirós
, Eva Alonso
,
Mostafa Rateb
, Wael E. Houssen
, Rainer Ebel
, Marcel Jaspars
, Amparo Alfonso
, Luís M. Botana
Research output
:
Contribution to journal
›
Article
›
peer-review
53
Link opens in a new tab
Citations (Scopus)
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Keyphrases
Alzheimer's Disease
100%
Gracilin
100%
ERK Inhibition
33%
Therapeutic Use
16%
Antioxidant
16%
Potential Therapeutics
16%
Drug Screening
16%
Neurodegenerative Diseases
16%
In Vivo Assay
16%
Oxidative Stress
16%
Bioactivity
16%
Drug Target
16%
Learning Memory
16%
Behavioral Tests
16%
In Vitro Assay
16%
Neuroblastoma
16%
Tau Phosphorylation
16%
Metabolism Study
16%
Alzheimer's Disease Model
16%
SH-SY5Y Cells
16%
β-site APP-cleaving Enzyme 1 (BACE1)
16%
Phosphorylated tau
16%
Cellular Models
16%
Tau Levels
16%
3xTg-AD
16%
Neurodegenerative Pathologies
16%
Mitochondrial Targeting
16%
Spatial Memory
16%
Intraperitoneal Injection
16%
Multi-target Approach
16%
Nrf2 Translocation
16%
Mitochondrial Dysfunction
16%
Positive Trend
16%
Anti-Alzheimer Drugs
16%
APP Metabolism
16%
Tau Hyperphosphorylation
16%
Diterpenoids
16%
Multitarget Drugs
16%
BACE1 Inhibition
16%
Medicine and Dentistry
Alzheimer's Disease
100%
Tau
50%
In Vitro
16%
Oxidative Stress
16%
Hyperphosphorylation
16%
SH-SY5Y
16%
Spatial Memory
16%
Cellular Model
16%
Antioxidant
16%
Ganglioneuroblastoma
16%
Transcription Factor Nrf2
16%
Diterpenoid
16%
Degenerative Disease
16%
Drug Screening
16%
Cell Line
16%
Amyloid Protein
16%
Mitochondrial Disorder
16%
Pharmacology, Toxicology and Pharmaceutical Science
Alzheimer's Disease
100%
Antioxidant
16%
Degenerative Disease
16%
Neuroblastoma
16%
Drug Screening
16%
Target Activity
16%
Transcription Factor Nrf2
16%
Diterpenoid
16%
Amyloid Protein
16%