Abstract
OBJECTIVE: To determine the clinical utility and the effect of sodium aurothiomalate (GSTM) on serum interleukin 6 (IL-6) levels in patients with rheumatoid arthritis (RA).
METHODS: Open prospective study of 50 patients with RA treated with GSTM. Serum IL-6 measured by bioassay.
RESULTS: IL-6 showed correlations with Ritchie articular index, duration of morning stiffness and C-reactive protein. GSTM significantly reduced IL-6 levels.
CONCLUSIONS: IL-6 is a potentially useful additional indicator of disease activity in RA and is modulated by GSTM.
| Original language | English |
|---|---|
| Pages (from-to) | 630-3 |
| Number of pages | 4 |
| Journal | Clinical Rheumatology |
| Volume | 20 |
| Issue number | 4 |
| Publication status | Published - Apr 1993 |
| Externally published | Yes |
Keywords
- Arthritis, Rheumatoid
- Biological Assay
- Female
- Gold Sodium Thiomalate
- Humans
- Interleukin-6
- Male
- Reference Values