Global and regional left ventricular circumferential strain during incremental cycling and isometric knee extension exercise

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Abstract

BackgroundThe objective of this study was to investigate left ventricular (LV) circumferential strain responses to incremental cycling and isometric knee extension exercises.
MethodsTwenty‐six healthy male participants (age = 30 ± 6 years) were used to study LV global (GCS) and regional circumferential strain at the apex (ACS) and base (BCS) during incremental cycling at 30% and 60% work rate maximum (Wmax) and short‐duration (15 seconds contractions) isometric knee extensions at 40% and 75% maximum voluntary contraction (MVC) using two‐dimensional speckle tracking echocardiography.
ResultsDuring cycling (n = 22), GCS increased progressively from rest to 60% Wmax (−22.85 ± 3.26% to −29.87 ± 2.59%, P < .01). ACS increased from rest to 30% Wmax (−26.29 ± 4.84% to −36.84 ± 6.94%, P < .01) and then remained unchanged to 60% Wmax (−40.72 ± 4.06%, P = .068). BCS decreased from rest to 30% Wmax (−19.41 ± 2.79 to −17.51 ± 4.66%, P = .05) and then remained unchanged to 60% Wmax. During isometric knee extension (n = 23), GCS decreased from rest to 40% MVC (−22.63 ± 3.46 to −20.10 ± 2.78%, P < .05) and then remained unchanged to 75% MVC. Similarly, BCS decreased from rest to 40% MVC (−19.21 ± 2.58% to −13.55 ± 3.45%, P < .01) and then remained unchanged, whereas ACS did not change with exercise intensity (rest, −26.05 ± 5.34%; 40% MVC, −26.64 ± 4.53% and 75% MVC −27.22 ± 5.34%, all P > .05).
ConclusionGlobal circumferential strain increased stepwise during incremental cycling, mediated by the apex with trivial changes at the base. In contrast, GCS decreased during the isometric knee extension to 40% MVC and then plateaued, due to decreased BCS as ACS was maintained. A novel finding is that the GCS response appears to be exercise modality dependant and is the consequence of region‐specific changes.
Original languageEnglish
Pages (from-to)1149-1156
Number of pages8
JournalEchocardiography
Volume35
Issue number8
Early online date16 Apr 2018
DOIs
Publication statusPublished - 1 Aug 2018

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Knee
Exercise
Isometric Contraction
Echocardiography
Healthy Volunteers

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@article{a3cee1194651499dadbdb1cb30734843,
title = "Global and regional left ventricular circumferential strain during incremental cycling and isometric knee extension exercise",
abstract = "BackgroundThe objective of this study was to investigate left ventricular (LV) circumferential strain responses to incremental cycling and isometric knee extension exercises.MethodsTwenty‐six healthy male participants (age = 30 ± 6 years) were used to study LV global (GCS) and regional circumferential strain at the apex (ACS) and base (BCS) during incremental cycling at 30{\%} and 60{\%} work rate maximum (Wmax) and short‐duration (15 seconds contractions) isometric knee extensions at 40{\%} and 75{\%} maximum voluntary contraction (MVC) using two‐dimensional speckle tracking echocardiography.ResultsDuring cycling (n = 22), GCS increased progressively from rest to 60{\%} Wmax (−22.85 ± 3.26{\%} to −29.87 ± 2.59{\%}, P < .01). ACS increased from rest to 30{\%} Wmax (−26.29 ± 4.84{\%} to −36.84 ± 6.94{\%}, P < .01) and then remained unchanged to 60{\%} Wmax (−40.72 ± 4.06{\%}, P = .068). BCS decreased from rest to 30{\%} Wmax (−19.41 ± 2.79 to −17.51 ± 4.66{\%}, P = .05) and then remained unchanged to 60{\%} Wmax. During isometric knee extension (n = 23), GCS decreased from rest to 40{\%} MVC (−22.63 ± 3.46 to −20.10 ± 2.78{\%}, P < .05) and then remained unchanged to 75{\%} MVC. Similarly, BCS decreased from rest to 40{\%} MVC (−19.21 ± 2.58{\%} to −13.55 ± 3.45{\%}, P < .01) and then remained unchanged, whereas ACS did not change with exercise intensity (rest, −26.05 ± 5.34{\%}; 40{\%} MVC, −26.64 ± 4.53{\%} and 75{\%} MVC −27.22 ± 5.34{\%}, all P > .05).ConclusionGlobal circumferential strain increased stepwise during incremental cycling, mediated by the apex with trivial changes at the base. In contrast, GCS decreased during the isometric knee extension to 40{\%} MVC and then plateaued, due to decreased BCS as ACS was maintained. A novel finding is that the GCS response appears to be exercise modality dependant and is the consequence of region‐specific changes.",
author = "Alexander Beaumont and Nicholas Sculthorpe and John Hough and Viswanath Unnithan and Joanna Richards",
year = "2018",
month = "8",
day = "1",
doi = "10.1111/echo.13894",
language = "English",
volume = "35",
pages = "1149--1156",
journal = "Echocardiography",
issn = "0742-2822",
publisher = "John Wiley & Sons, Inc.",
number = "8",

}

TY - JOUR

T1 - Global and regional left ventricular circumferential strain during incremental cycling and isometric knee extension exercise

AU - Beaumont, Alexander

AU - Sculthorpe, Nicholas

AU - Hough, John

AU - Unnithan, Viswanath

AU - Richards, Joanna

PY - 2018/8/1

Y1 - 2018/8/1

N2 - BackgroundThe objective of this study was to investigate left ventricular (LV) circumferential strain responses to incremental cycling and isometric knee extension exercises.MethodsTwenty‐six healthy male participants (age = 30 ± 6 years) were used to study LV global (GCS) and regional circumferential strain at the apex (ACS) and base (BCS) during incremental cycling at 30% and 60% work rate maximum (Wmax) and short‐duration (15 seconds contractions) isometric knee extensions at 40% and 75% maximum voluntary contraction (MVC) using two‐dimensional speckle tracking echocardiography.ResultsDuring cycling (n = 22), GCS increased progressively from rest to 60% Wmax (−22.85 ± 3.26% to −29.87 ± 2.59%, P < .01). ACS increased from rest to 30% Wmax (−26.29 ± 4.84% to −36.84 ± 6.94%, P < .01) and then remained unchanged to 60% Wmax (−40.72 ± 4.06%, P = .068). BCS decreased from rest to 30% Wmax (−19.41 ± 2.79 to −17.51 ± 4.66%, P = .05) and then remained unchanged to 60% Wmax. During isometric knee extension (n = 23), GCS decreased from rest to 40% MVC (−22.63 ± 3.46 to −20.10 ± 2.78%, P < .05) and then remained unchanged to 75% MVC. Similarly, BCS decreased from rest to 40% MVC (−19.21 ± 2.58% to −13.55 ± 3.45%, P < .01) and then remained unchanged, whereas ACS did not change with exercise intensity (rest, −26.05 ± 5.34%; 40% MVC, −26.64 ± 4.53% and 75% MVC −27.22 ± 5.34%, all P > .05).ConclusionGlobal circumferential strain increased stepwise during incremental cycling, mediated by the apex with trivial changes at the base. In contrast, GCS decreased during the isometric knee extension to 40% MVC and then plateaued, due to decreased BCS as ACS was maintained. A novel finding is that the GCS response appears to be exercise modality dependant and is the consequence of region‐specific changes.

AB - BackgroundThe objective of this study was to investigate left ventricular (LV) circumferential strain responses to incremental cycling and isometric knee extension exercises.MethodsTwenty‐six healthy male participants (age = 30 ± 6 years) were used to study LV global (GCS) and regional circumferential strain at the apex (ACS) and base (BCS) during incremental cycling at 30% and 60% work rate maximum (Wmax) and short‐duration (15 seconds contractions) isometric knee extensions at 40% and 75% maximum voluntary contraction (MVC) using two‐dimensional speckle tracking echocardiography.ResultsDuring cycling (n = 22), GCS increased progressively from rest to 60% Wmax (−22.85 ± 3.26% to −29.87 ± 2.59%, P < .01). ACS increased from rest to 30% Wmax (−26.29 ± 4.84% to −36.84 ± 6.94%, P < .01) and then remained unchanged to 60% Wmax (−40.72 ± 4.06%, P = .068). BCS decreased from rest to 30% Wmax (−19.41 ± 2.79 to −17.51 ± 4.66%, P = .05) and then remained unchanged to 60% Wmax. During isometric knee extension (n = 23), GCS decreased from rest to 40% MVC (−22.63 ± 3.46 to −20.10 ± 2.78%, P < .05) and then remained unchanged to 75% MVC. Similarly, BCS decreased from rest to 40% MVC (−19.21 ± 2.58% to −13.55 ± 3.45%, P < .01) and then remained unchanged, whereas ACS did not change with exercise intensity (rest, −26.05 ± 5.34%; 40% MVC, −26.64 ± 4.53% and 75% MVC −27.22 ± 5.34%, all P > .05).ConclusionGlobal circumferential strain increased stepwise during incremental cycling, mediated by the apex with trivial changes at the base. In contrast, GCS decreased during the isometric knee extension to 40% MVC and then plateaued, due to decreased BCS as ACS was maintained. A novel finding is that the GCS response appears to be exercise modality dependant and is the consequence of region‐specific changes.

U2 - 10.1111/echo.13894

DO - 10.1111/echo.13894

M3 - Article

VL - 35

SP - 1149

EP - 1156

JO - Echocardiography

JF - Echocardiography

SN - 0742-2822

IS - 8

ER -