Exercise performance, muscle damage and oxidative stress: a role for antioxidants?

Julien S. Baker, Bruce Davies

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A free radical is a molecule with an unpaired electron in its outer orbital and is produced during normal cellular metabolism. High levels of radicals can damage cells by reacting with cellular components (e.g., proteins and lipids). This form of damage is called oxidation and can result in a lethal injury to cells. Given that radicals are produced during normal metabolism, it is not surprising that cells contain antioxidants (molecules that eliminate radicals) to reduce the risk of radical-mediated injury. Two major classes of antioxidants work together to reduce the potentially harmful effects of radicals: 1) enzymatic antioxidants and 2) non-enzymatic antioxidants. Key antioxidant enzymes include superoxide dismutase, glutathione peroxidase, and catalase. These enzymes are manufactured in the cell and cannot be obtained through dietary supplementation. Important non-enzymatic antioxidants include vitamins E and C, and betacarotene. These antioxidants are included in many foods and can also be obtained through dietary supplements. Vitamin E and beta-carotene are lipid-soluble antioxidants and protect cell membranes from radical damage. Vitamin C is a water-soluble antioxidant and works in conjunction with vitamin E to protect both lipids and proteins in the cell from radical damage
Original languageEnglish
Title of host publicationAdvances in Medicine and Biology
Subtitle of host publicationVolume 12
EditorsLeon V. Berhardt
PublisherNova Science Publishers
Pages107-115
Number of pages9
Volume12
ISBN (Print)9781617611421
Publication statusPublished - 2010

Publication series

NameAdvances in Medicine and Biology
PublisherNova Science Publishers
Volume12

Fingerprint

Oxidative Stress
Antioxidants
Muscles
Vitamin E
beta Carotene
Dietary Supplements
Lipids
Ascorbic Acid
Wounds and Injuries
Enzymes
Glutathione Peroxidase
Catalase
Superoxide Dismutase
Free Radicals
Proteins
Cell Membrane
Electrons
Food
Water

Cite this

Baker, J. S., & Davies, B. (2010). Exercise performance, muscle damage and oxidative stress: a role for antioxidants? In L. V. Berhardt (Ed.), Advances in Medicine and Biology: Volume 12 (Vol. 12, pp. 107-115). (Advances in Medicine and Biology; Vol. 12). Nova Science Publishers.
Baker, Julien S. ; Davies, Bruce. / Exercise performance, muscle damage and oxidative stress : a role for antioxidants?. Advances in Medicine and Biology: Volume 12. editor / Leon V. Berhardt. Vol. 12 Nova Science Publishers, 2010. pp. 107-115 (Advances in Medicine and Biology).
@inbook{dc27cd58e5c240ac9856dbf51eb30580,
title = "Exercise performance, muscle damage and oxidative stress: a role for antioxidants?",
abstract = "A free radical is a molecule with an unpaired electron in its outer orbital and is produced during normal cellular metabolism. High levels of radicals can damage cells by reacting with cellular components (e.g., proteins and lipids). This form of damage is called oxidation and can result in a lethal injury to cells. Given that radicals are produced during normal metabolism, it is not surprising that cells contain antioxidants (molecules that eliminate radicals) to reduce the risk of radical-mediated injury. Two major classes of antioxidants work together to reduce the potentially harmful effects of radicals: 1) enzymatic antioxidants and 2) non-enzymatic antioxidants. Key antioxidant enzymes include superoxide dismutase, glutathione peroxidase, and catalase. These enzymes are manufactured in the cell and cannot be obtained through dietary supplementation. Important non-enzymatic antioxidants include vitamins E and C, and betacarotene. These antioxidants are included in many foods and can also be obtained through dietary supplements. Vitamin E and beta-carotene are lipid-soluble antioxidants and protect cell membranes from radical damage. Vitamin C is a water-soluble antioxidant and works in conjunction with vitamin E to protect both lipids and proteins in the cell from radical damage",
author = "Baker, {Julien S.} and Bruce Davies",
year = "2010",
language = "English",
isbn = "9781617611421",
volume = "12",
series = "Advances in Medicine and Biology",
publisher = "Nova Science Publishers",
pages = "107--115",
editor = "Berhardt, {Leon V.}",
booktitle = "Advances in Medicine and Biology",
address = "United States",

}

Baker, JS & Davies, B 2010, Exercise performance, muscle damage and oxidative stress: a role for antioxidants? in LV Berhardt (ed.), Advances in Medicine and Biology: Volume 12. vol. 12, Advances in Medicine and Biology, vol. 12, Nova Science Publishers, pp. 107-115.

Exercise performance, muscle damage and oxidative stress : a role for antioxidants? / Baker, Julien S.; Davies, Bruce.

Advances in Medicine and Biology: Volume 12. ed. / Leon V. Berhardt. Vol. 12 Nova Science Publishers, 2010. p. 107-115 (Advances in Medicine and Biology; Vol. 12).

Research output: Chapter in Book/Report/Conference proceedingChapter

TY - CHAP

T1 - Exercise performance, muscle damage and oxidative stress

T2 - a role for antioxidants?

AU - Baker, Julien S.

AU - Davies, Bruce

PY - 2010

Y1 - 2010

N2 - A free radical is a molecule with an unpaired electron in its outer orbital and is produced during normal cellular metabolism. High levels of radicals can damage cells by reacting with cellular components (e.g., proteins and lipids). This form of damage is called oxidation and can result in a lethal injury to cells. Given that radicals are produced during normal metabolism, it is not surprising that cells contain antioxidants (molecules that eliminate radicals) to reduce the risk of radical-mediated injury. Two major classes of antioxidants work together to reduce the potentially harmful effects of radicals: 1) enzymatic antioxidants and 2) non-enzymatic antioxidants. Key antioxidant enzymes include superoxide dismutase, glutathione peroxidase, and catalase. These enzymes are manufactured in the cell and cannot be obtained through dietary supplementation. Important non-enzymatic antioxidants include vitamins E and C, and betacarotene. These antioxidants are included in many foods and can also be obtained through dietary supplements. Vitamin E and beta-carotene are lipid-soluble antioxidants and protect cell membranes from radical damage. Vitamin C is a water-soluble antioxidant and works in conjunction with vitamin E to protect both lipids and proteins in the cell from radical damage

AB - A free radical is a molecule with an unpaired electron in its outer orbital and is produced during normal cellular metabolism. High levels of radicals can damage cells by reacting with cellular components (e.g., proteins and lipids). This form of damage is called oxidation and can result in a lethal injury to cells. Given that radicals are produced during normal metabolism, it is not surprising that cells contain antioxidants (molecules that eliminate radicals) to reduce the risk of radical-mediated injury. Two major classes of antioxidants work together to reduce the potentially harmful effects of radicals: 1) enzymatic antioxidants and 2) non-enzymatic antioxidants. Key antioxidant enzymes include superoxide dismutase, glutathione peroxidase, and catalase. These enzymes are manufactured in the cell and cannot be obtained through dietary supplementation. Important non-enzymatic antioxidants include vitamins E and C, and betacarotene. These antioxidants are included in many foods and can also be obtained through dietary supplements. Vitamin E and beta-carotene are lipid-soluble antioxidants and protect cell membranes from radical damage. Vitamin C is a water-soluble antioxidant and works in conjunction with vitamin E to protect both lipids and proteins in the cell from radical damage

M3 - Chapter

SN - 9781617611421

VL - 12

T3 - Advances in Medicine and Biology

SP - 107

EP - 115

BT - Advances in Medicine and Biology

A2 - Berhardt, Leon V.

PB - Nova Science Publishers

ER -

Baker JS, Davies B. Exercise performance, muscle damage and oxidative stress: a role for antioxidants? In Berhardt LV, editor, Advances in Medicine and Biology: Volume 12. Vol. 12. Nova Science Publishers. 2010. p. 107-115. (Advances in Medicine and Biology).