Estimating the variability in the risk of infection for hepatitis C in the Glasgow injecting drug user population

A. J. Sutton, S. A. McDonald, N. Palmateer, A. Taylor, S. J. Hutchinson

Research output: Contribution to journalArticle

Abstract

Glasgow (Scotland's largest city) has a high prevalence of injecting drug use and has one of the highest prevalences of hepatitis C virus (HCV) infection in injecting drug users (IDUs) in Western Europe. HCV prevalence data from surveys of Glasgow's IDUs from 1990 to 2007 were utilized and a model was applied that described the prevalence of HCV as a function of the rate (force) of infection. Force-of-infection estimates for HCV that may vary over time and injecting career length over a range of variables were investigated. New initiates to injecting were found to be at increased risk of HCV infection, with being recruited from a street location and reporting injecting in prison leading to a significant increase in the risk of infection in new initiates. These results indicate areas of importance for the planning of public health measures that target the IDU population.
Original languageEnglish
Pages (from-to)2190-2198
JournalEpidemiology and Infection
Volume140
Issue number12
DOIs
Publication statusPublished - Dec 2012

Keywords

  • Hepatitis C
  • incidence
  • infectious disease
  • injecting drug users (IDUs)
  • mathematical modelling

Cite this

Sutton, A. J. ; McDonald, S. A. ; Palmateer, N. ; Taylor, A. ; Hutchinson, S. J. / Estimating the variability in the risk of infection for hepatitis C in the Glasgow injecting drug user population. In: Epidemiology and Infection. 2012 ; Vol. 140, No. 12. pp. 2190-2198.
@article{6bc49c0d30714aa5a0945bf2f6f8923b,
title = "Estimating the variability in the risk of infection for hepatitis C in the Glasgow injecting drug user population",
abstract = "Glasgow (Scotland's largest city) has a high prevalence of injecting drug use and has one of the highest prevalences of hepatitis C virus (HCV) infection in injecting drug users (IDUs) in Western Europe. HCV prevalence data from surveys of Glasgow's IDUs from 1990 to 2007 were utilized and a model was applied that described the prevalence of HCV as a function of the rate (force) of infection. Force-of-infection estimates for HCV that may vary over time and injecting career length over a range of variables were investigated. New initiates to injecting were found to be at increased risk of HCV infection, with being recruited from a street location and reporting injecting in prison leading to a significant increase in the risk of infection in new initiates. These results indicate areas of importance for the planning of public health measures that target the IDU population.",
keywords = "Hepatitis C, incidence, infectious disease, injecting drug users (IDUs), mathematical modelling",
author = "Sutton, {A. J.} and McDonald, {S. A.} and N. Palmateer and A. Taylor and Hutchinson, {S. J.}",
year = "2012",
month = "12",
doi = "10.1017/S0950268812000489",
language = "English",
volume = "140",
pages = "2190--2198",
journal = "Epidemiology and Infection",
issn = "0950-2688",
publisher = "Cambridge University Press",
number = "12",

}

Estimating the variability in the risk of infection for hepatitis C in the Glasgow injecting drug user population. / Sutton, A. J.; McDonald, S. A.; Palmateer, N.; Taylor, A.; Hutchinson, S. J.

In: Epidemiology and Infection, Vol. 140, No. 12, 12.2012, p. 2190-2198.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Estimating the variability in the risk of infection for hepatitis C in the Glasgow injecting drug user population

AU - Sutton, A. J.

AU - McDonald, S. A.

AU - Palmateer, N.

AU - Taylor, A.

AU - Hutchinson, S. J.

PY - 2012/12

Y1 - 2012/12

N2 - Glasgow (Scotland's largest city) has a high prevalence of injecting drug use and has one of the highest prevalences of hepatitis C virus (HCV) infection in injecting drug users (IDUs) in Western Europe. HCV prevalence data from surveys of Glasgow's IDUs from 1990 to 2007 were utilized and a model was applied that described the prevalence of HCV as a function of the rate (force) of infection. Force-of-infection estimates for HCV that may vary over time and injecting career length over a range of variables were investigated. New initiates to injecting were found to be at increased risk of HCV infection, with being recruited from a street location and reporting injecting in prison leading to a significant increase in the risk of infection in new initiates. These results indicate areas of importance for the planning of public health measures that target the IDU population.

AB - Glasgow (Scotland's largest city) has a high prevalence of injecting drug use and has one of the highest prevalences of hepatitis C virus (HCV) infection in injecting drug users (IDUs) in Western Europe. HCV prevalence data from surveys of Glasgow's IDUs from 1990 to 2007 were utilized and a model was applied that described the prevalence of HCV as a function of the rate (force) of infection. Force-of-infection estimates for HCV that may vary over time and injecting career length over a range of variables were investigated. New initiates to injecting were found to be at increased risk of HCV infection, with being recruited from a street location and reporting injecting in prison leading to a significant increase in the risk of infection in new initiates. These results indicate areas of importance for the planning of public health measures that target the IDU population.

KW - Hepatitis C

KW - incidence

KW - infectious disease

KW - injecting drug users (IDUs)

KW - mathematical modelling

U2 - 10.1017/S0950268812000489

DO - 10.1017/S0950268812000489

M3 - Article

VL - 140

SP - 2190

EP - 2198

JO - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

IS - 12

ER -