Electrocardiogram-based timings cause systematic errors in vascular strain measures: a method for error correction and estimation of pulse transit time

Nicholas Sculthorpe*, Amy Campbell, Alexander Beaumont

*Corresponding author for this work

Research output: Contribution to journalArticle


Speckle-tracking ultrasonography has been applied to the assessment of circumferential strain (ɛ) and strain rate (SR) of the common carotid artery (CCA).1-5 Originally developed for echocardiography,6 the analysis of ɛ is tethered to key points of the electrocardiogram (ECG). Thus, to prevent measurement drift, speckle-tracking ultrasonography software assumes no deformation (i.e., 0% ɛ) at the start of the cardiac cycle defined by the QRS wave. However, the pressure wave will take some time to travel from the aortic valve to the insonated section of vasculature, meaning vascular expansion and recoil occur shortly after ventricular systole.
Original languageEnglish
JournalJournal of the American Society of Echocardiography
Early online date12 Mar 2020
Publication statusE-pub ahead of print - 12 Mar 2020


  • Short report
  • Speckle tracking
  • Echocardiography

Cite this