Diagnostic performance of Body Mass Index, Waist Circumference and the Waist-to-Height Ratio for identifying cardiometabolic risk in Scottish pre-adolescents

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Abstract

Background: Limited studies have examined the diagnostic performance of body mass index (BMI), waist circumference (WC) or waist to height ratio (WHtR) for identifying cardiometabolic risk (increased clustered glucose, triglycerides, mean arterial pressure and inv-HDL-cholesterol) in pre-adolescent youth. Aim: To compare the utility of BMI, WC and WHtR as predictors of cardiometabolic risk (CMR) in Scottish pre-adolescent children. Subjects and Methods: A cross-sectional analysis of 223 Scottish children (55.2% boys, mean age 8.4 years) was undertaken. BMI, WC and WHtR were used as exposure variables within multivariate logistic regression analysis and ROC analysis to examine the utility of these anthropometrical indices in identifying those at cardiometabolic risk. Results: Individuals with an elevated WHtR, WC and BMI were 3.51 (95% CI: 1.71-7.23; P < 0.001); 2.34 (95% CI: 1.35-4.06; P= 0.002) and 2.59 (95% CI: 1.42-4.73; P = 0.002) times more likely to be at cardiometabolic risk. The areas under the curves [AUC] to identify children with cardiometabolic risk were significant and similar among anthropometric indices (AUC’s = 0.60 - 0.65). When stratified by BMI, both WC and WHtR demonstrated a fair to good ability for identifying those at cardiometabolic risk (AUC = 0.75 - 0.81). Conclusions: Findings suggest that the combination of BMI with either WC or WHtR may provide an added benefit in the assessment of cardiometabolic risk amongst pre-adolescents.
Original languageEnglish
Pages (from-to)297-302
JournalAnnals of Human Biology
Volume44
Issue number4
Early online date6 Nov 2016
DOIs
Publication statusE-pub ahead of print - 6 Nov 2016

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Waist Circumference
Body Mass Index
Area Under Curve
ROC Curve
HDL Cholesterol
Waist-Height Ratio
Arterial Pressure
Triglycerides
Cross-Sectional Studies
Logistic Models
Regression Analysis
Glucose

Keywords

  • Weight status
  • Youth
  • Obesity
  • Cardiometabolic risk

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@article{2d48e635e4d44a438059336c70f2b323,
title = "Diagnostic performance of Body Mass Index, Waist Circumference and the Waist-to-Height Ratio for identifying cardiometabolic risk in Scottish pre-adolescents",
abstract = "Background: Limited studies have examined the diagnostic performance of body mass index (BMI), waist circumference (WC) or waist to height ratio (WHtR) for identifying cardiometabolic risk (increased clustered glucose, triglycerides, mean arterial pressure and inv-HDL-cholesterol) in pre-adolescent youth. Aim: To compare the utility of BMI, WC and WHtR as predictors of cardiometabolic risk (CMR) in Scottish pre-adolescent children. Subjects and Methods: A cross-sectional analysis of 223 Scottish children (55.2{\%} boys, mean age 8.4 years) was undertaken. BMI, WC and WHtR were used as exposure variables within multivariate logistic regression analysis and ROC analysis to examine the utility of these anthropometrical indices in identifying those at cardiometabolic risk. Results: Individuals with an elevated WHtR, WC and BMI were 3.51 (95{\%} CI: 1.71-7.23; P < 0.001); 2.34 (95{\%} CI: 1.35-4.06; P= 0.002) and 2.59 (95{\%} CI: 1.42-4.73; P = 0.002) times more likely to be at cardiometabolic risk. The areas under the curves [AUC] to identify children with cardiometabolic risk were significant and similar among anthropometric indices (AUC’s = 0.60 - 0.65). When stratified by BMI, both WC and WHtR demonstrated a fair to good ability for identifying those at cardiometabolic risk (AUC = 0.75 - 0.81). Conclusions: Findings suggest that the combination of BMI with either WC or WHtR may provide an added benefit in the assessment of cardiometabolic risk amongst pre-adolescents.",
keywords = "Weight status, Youth, Obesity, Cardiometabolic risk",
author = "Duncan Buchan and Gillian McLellan and Samantha Donnelly and Rosemary Arthur",
year = "2016",
month = "11",
day = "6",
doi = "10.1080/03014460.2016.1247911",
language = "English",
volume = "44",
pages = "297--302",
journal = "Annals of Human Biology",
issn = "0301-4460",
publisher = "Taylor & Francis",
number = "4",

}

TY - JOUR

T1 - Diagnostic performance of Body Mass Index, Waist Circumference and the Waist-to-Height Ratio for identifying cardiometabolic risk in Scottish pre-adolescents

AU - Buchan, Duncan

AU - McLellan, Gillian

AU - Donnelly, Samantha

AU - Arthur, Rosemary

PY - 2016/11/6

Y1 - 2016/11/6

N2 - Background: Limited studies have examined the diagnostic performance of body mass index (BMI), waist circumference (WC) or waist to height ratio (WHtR) for identifying cardiometabolic risk (increased clustered glucose, triglycerides, mean arterial pressure and inv-HDL-cholesterol) in pre-adolescent youth. Aim: To compare the utility of BMI, WC and WHtR as predictors of cardiometabolic risk (CMR) in Scottish pre-adolescent children. Subjects and Methods: A cross-sectional analysis of 223 Scottish children (55.2% boys, mean age 8.4 years) was undertaken. BMI, WC and WHtR were used as exposure variables within multivariate logistic regression analysis and ROC analysis to examine the utility of these anthropometrical indices in identifying those at cardiometabolic risk. Results: Individuals with an elevated WHtR, WC and BMI were 3.51 (95% CI: 1.71-7.23; P < 0.001); 2.34 (95% CI: 1.35-4.06; P= 0.002) and 2.59 (95% CI: 1.42-4.73; P = 0.002) times more likely to be at cardiometabolic risk. The areas under the curves [AUC] to identify children with cardiometabolic risk were significant and similar among anthropometric indices (AUC’s = 0.60 - 0.65). When stratified by BMI, both WC and WHtR demonstrated a fair to good ability for identifying those at cardiometabolic risk (AUC = 0.75 - 0.81). Conclusions: Findings suggest that the combination of BMI with either WC or WHtR may provide an added benefit in the assessment of cardiometabolic risk amongst pre-adolescents.

AB - Background: Limited studies have examined the diagnostic performance of body mass index (BMI), waist circumference (WC) or waist to height ratio (WHtR) for identifying cardiometabolic risk (increased clustered glucose, triglycerides, mean arterial pressure and inv-HDL-cholesterol) in pre-adolescent youth. Aim: To compare the utility of BMI, WC and WHtR as predictors of cardiometabolic risk (CMR) in Scottish pre-adolescent children. Subjects and Methods: A cross-sectional analysis of 223 Scottish children (55.2% boys, mean age 8.4 years) was undertaken. BMI, WC and WHtR were used as exposure variables within multivariate logistic regression analysis and ROC analysis to examine the utility of these anthropometrical indices in identifying those at cardiometabolic risk. Results: Individuals with an elevated WHtR, WC and BMI were 3.51 (95% CI: 1.71-7.23; P < 0.001); 2.34 (95% CI: 1.35-4.06; P= 0.002) and 2.59 (95% CI: 1.42-4.73; P = 0.002) times more likely to be at cardiometabolic risk. The areas under the curves [AUC] to identify children with cardiometabolic risk were significant and similar among anthropometric indices (AUC’s = 0.60 - 0.65). When stratified by BMI, both WC and WHtR demonstrated a fair to good ability for identifying those at cardiometabolic risk (AUC = 0.75 - 0.81). Conclusions: Findings suggest that the combination of BMI with either WC or WHtR may provide an added benefit in the assessment of cardiometabolic risk amongst pre-adolescents.

KW - Weight status

KW - Youth

KW - Obesity

KW - Cardiometabolic risk

U2 - 10.1080/03014460.2016.1247911

DO - 10.1080/03014460.2016.1247911

M3 - Article

VL - 44

SP - 297

EP - 302

JO - Annals of Human Biology

JF - Annals of Human Biology

SN - 0301-4460

IS - 4

ER -