Depression, anxiety, and stress among hangover-sensitive and hangover-resistant drinkers

Andy J. Kim, Agnese Merlo, Marlou Mackus, Gillian Bruce, Sean J. Johnson, Chris Alford, Simon B. Sherry, Sherry H. Stewart, Joris C. Verster *

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
7 Downloads (Pure)


This study investigated potential differences in baseline (i.e., non-hangover-related) levels of depression, anxiety, and stress between individuals who are sensitive to and those resistant to hangovers after consuming alcohol. Participants included 5111 university students from the Netherlands and the U.K., including 3205 hangover-sensitive and 1906 hangover-resistant drinkers. All participants completed surveys on their demographics, alcohol consumption, and hangover susceptibility (whether they experienced a hangover in the past 12 months), as well as their baseline levels of depression, anxiety, and stress on the DASS-21 scale. The results showed that hangover-sensitive drinkers had significantly higher levels of anxiety and stress, but not depression, compared to hangover-resistant drinkers. However, the observed differences between the two groups were small, with a magnitude of less than 1 out of 42 points on the DASS-21 anxiety and stress subscales, and are thus unlikely to be clinically meaningful.
Original languageEnglish
Article number2766
Number of pages8
JournalJournal of Clinical Medicine
Issue number8
Publication statusPublished - 7 Apr 2023


  • alcohol
  • hangover
  • resistance
  • anxiety
  • stress
  • depression


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