CO2 laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion

Jonathan Lawrence; Liang Hao

doi:10.2351/1.5060775

CO₂ laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion

Jonathan Lawrence, Liang Hao

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Osteoblast cells were used in an in vitro test to examine changes in cell adhesion on a magnesia partially stabilised zirconia (MgO-PSZ) bioceramic after CO₂ laser treatment. The surface roughness, microstructure, crystal size and surface energy of untreated and CO₂ laser treated samples were fully characterized. After 24 h cell incubation, no cells were observed on the untreated MgO-PSZ, whereas cells were seen to have attached onto the CO₂ laser treated MgO-PSZ and exhibited spreading and good attachment. Moreover, the cell coverage density implied an increase in cell proliferation with increasing CO₂ laser power density. Enhancement of the surface energy of the MgO-PSZ, especially its polar component, caused by the CO₂ laser treatment was found to play a significant role in the initial cell attachment process, thereby leading to enhanced cell growth. Also, the change in topography induced by the CO₂ laser treatment was identified as one of the factors influencing the osteoblast cell response.

Original language	English
Title of host publication	ICALEO® 2006
Subtitle of host publication	25th International Congress on Laser Materials Processing and Laser Microfabrication
Publisher	AIP Publishing
ISBN (Electronic)	9780912035857
DOIs	https://doi.org/10.2351/1.5060775
Publication status	Published - 31 Oct 2006
Externally published	Yes
Event	25th International Congress on Laser Materials Processing and Laser Microfabrication - Scottsdale, United States Duration: 30 Oct 2006 → 2 Nov 2006

Conference

Conference	25th International Congress on Laser Materials Processing and Laser Microfabrication
Abbreviated title	ICALEO® 2006
Country/Territory	United States
City	Scottsdale
Period	30/10/06 → 2/11/06

Access to Document

10.2351/1.5060775

Cite this

@inproceedings{0a0564ca73024667a312fa6af48a83de,

title = "CO2 laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion",

abstract = "Osteoblast cells were used in an in vitro test to examine changes in cell adhesion on a magnesia partially stabilised zirconia (MgO-PSZ) bioceramic after CO2 laser treatment. The surface roughness, microstructure, crystal size and surface energy of untreated and CO2 laser treated samples were fully characterized. After 24 h cell incubation, no cells were observed on the untreated MgO-PSZ, whereas cells were seen to have attached onto the CO2 laser treated MgO-PSZ and exhibited spreading and good attachment. Moreover, the cell coverage density implied an increase in cell proliferation with increasing CO2 laser power density. Enhancement of the surface energy of the MgO-PSZ, especially its polar component, caused by the CO2 laser treatment was found to play a significant role in the initial cell attachment process, thereby leading to enhanced cell growth. Also, the change in topography induced by the CO2 laser treatment was identified as one of the factors influencing the osteoblast cell response.",

author = "Jonathan Lawrence and Liang Hao",

year = "2006",

month = oct,

day = "31",

doi = "10.2351/1.5060775",

language = "English",

booktitle = "ICALEO{\textregistered} 2006",

publisher = "AIP Publishing",

address = "United States",

note = "25th International Congress on Laser Materials Processing and Laser Microfabrication, ICALEO{\textregistered} 2006 ; Conference date: 30-10-2006 Through 02-11-2006",

}

Lawrence, J & Hao, L 2006, CO₂ laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion. in ICALEO® 2006: 25th International Congress on Laser Materials Processing and Laser Microfabrication., 1506, AIP Publishing, 25th International Congress on Laser Materials Processing and Laser Microfabrication, Scottsdale, Arizona, United States, 30/10/06. https://doi.org/10.2351/1.5060775

CO₂ laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion. / Lawrence, Jonathan; Hao, Liang.
ICALEO® 2006: 25th International Congress on Laser Materials Processing and Laser Microfabrication. AIP Publishing, 2006. 1506.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - CO2 laser irradiation of a magnesia partially stabilized zirconia (MgO-PSZ) bioceramic and the subsequent improvements in human osteoblast cell adhesion

AU - Lawrence, Jonathan

AU - Hao, Liang

PY - 2006/10/31

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N2 - Osteoblast cells were used in an in vitro test to examine changes in cell adhesion on a magnesia partially stabilised zirconia (MgO-PSZ) bioceramic after CO2 laser treatment. The surface roughness, microstructure, crystal size and surface energy of untreated and CO2 laser treated samples were fully characterized. After 24 h cell incubation, no cells were observed on the untreated MgO-PSZ, whereas cells were seen to have attached onto the CO2 laser treated MgO-PSZ and exhibited spreading and good attachment. Moreover, the cell coverage density implied an increase in cell proliferation with increasing CO2 laser power density. Enhancement of the surface energy of the MgO-PSZ, especially its polar component, caused by the CO2 laser treatment was found to play a significant role in the initial cell attachment process, thereby leading to enhanced cell growth. Also, the change in topography induced by the CO2 laser treatment was identified as one of the factors influencing the osteoblast cell response.

AB - Osteoblast cells were used in an in vitro test to examine changes in cell adhesion on a magnesia partially stabilised zirconia (MgO-PSZ) bioceramic after CO2 laser treatment. The surface roughness, microstructure, crystal size and surface energy of untreated and CO2 laser treated samples were fully characterized. After 24 h cell incubation, no cells were observed on the untreated MgO-PSZ, whereas cells were seen to have attached onto the CO2 laser treated MgO-PSZ and exhibited spreading and good attachment. Moreover, the cell coverage density implied an increase in cell proliferation with increasing CO2 laser power density. Enhancement of the surface energy of the MgO-PSZ, especially its polar component, caused by the CO2 laser treatment was found to play a significant role in the initial cell attachment process, thereby leading to enhanced cell growth. Also, the change in topography induced by the CO2 laser treatment was identified as one of the factors influencing the osteoblast cell response.

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DO - 10.2351/1.5060775

M3 - Conference contribution

BT - ICALEO® 2006

PB - AIP Publishing

T2 - 25th International Congress on Laser Materials Processing and Laser Microfabrication

Y2 - 30 October 2006 through 2 November 2006