Aspergillus biofilms: clinical and industrial significance

Gordon Ramage, Ranjith Rajendran, Marcel Gutierrez-Correa, Brian L. Jones, Craig Williams

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

The biofilm phenotype is an increasingly important concept in mycological research. Recently, there has been a developing interest in whether Aspergillus species are truly able to form biofilms or not. Industrial mycologists have long been aware of biofilms and their benefit in fermentation processes, whereas clinically their role is uncertain. This review provides an update on the impact that Aspergillus biofilms have medically and industrially, and will discuss biofilm development, and our current understanding of its molecular basis. The role of exopolymeric substance and how this substance relates to antimicrobial recalcitrance will also be discussed.

Original languageEnglish
Pages (from-to)89-97
Number of pages9
JournalFEMS Microbiology Letters
Volume324
Issue number2
DOIs
Publication statusPublished - Nov 2011
Externally publishedYes

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Keywords

  • Animals
  • Anti-Bacterial Agents
  • Aspergillosis
  • Aspergillus niger
  • Biofilms
  • Humans
  • Industrial Microbiology
  • Adhesion
  • Review
  • Aspergillus fumigatus

Cite this

Ramage, G., Rajendran, R., Gutierrez-Correa, M., Jones, B. L., & Williams, C. (2011). Aspergillus biofilms: clinical and industrial significance. FEMS Microbiology Letters, 324(2), 89-97. https://doi.org/10.1111/j.1574-6968.2011.02381.x