An Introduction to Medicinal Chemistry

Graham Patrick

Research output: Book/ReportBook

Abstract

For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market?

An Introduction to Medicinal Chemistry, sixth edition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Part one of the book introduces the principles of drug action via targets such as receptors and enzymes. The book goes on to explore how drugs work at the molecular level (pharmacodynamics), and the processes involved in ensuring a drug meets its target (pharmacokinetics). Further sections cover the processes by which drugs are discovered and designed, and what has to happen before a drug can be made available to the public. The book concludes with a selection of current topics in medicinal chemistry, and a discussion of various key drug groups. The subject is brought to life throughout by engaging case studies highlighting particular drugs and the stories behind their discovery and development.
Original languageEnglish
PublisherOxford University Press
Number of pages912
Edition6th
ISBN (Print)9780198749691
Publication statusPublished - 2017

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Keywords

  • Medicinal Chemistry
  • Drug Design
  • Drug Discovery
  • Drug Development
  • Drug Optimisation
  • Pharmaceuticals

Cite this

Patrick, G. (2017). An Introduction to Medicinal Chemistry. (6th ed.) Oxford University Press.