Acute resistance exercise program variables and subsequent hormonal response

Lawrence D. Hayes, Gordon F. Bickerstaff, Julien Baker

Research output: Contribution to journalArticlepeer-review


Resistance Exercise (RE) is a widely practiced activity both in leisure time and in training periods for competitive athletes. Recent advanced in molecular biology and muscle physiology has elucidated some of the mechanisms that regulate muscle growth. However, these molecular advances require application in acute program variables of RE. Therefore, we present an updated paradigm of resistance exercise variables and the effect manipulating these has on signalling pathways and hormonal response to optimise RE adaptations. We herein explore the effect of altering (i) choice of exercise; (ii) order of exercises performed; (iii) load (weight/resistance); (iv) volume (i.e. repetitions x sets x load) and (v) rest period between sets. Manipulating these variables has a consequential effect on signalling pathways, hormone response and neural adaptations that may influence protein synthesis and therefore gradual protein accretion leading to increased muscle size and strength.
Original languageEnglish
Article number1000125
Number of pages10
JournalJournal of Sports Medicine & Doping Studies
Publication statusPublished - Aug 2013


Dive into the research topics of 'Acute resistance exercise program variables and subsequent hormonal response'. Together they form a unique fingerprint.

Cite this