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  • Anne Crilly
2020

Characterisation of exosomes isolated by ultracentrifugation from human primary bronchial epithelial cells

Downey, N., McGarvey, L., Martin, S. L., Crilly, A. & Lundy, F. T., 3 Feb 2020, In : Lung. 198, 1, p. 36-36 1 p.

Research output: Contribution to journalMeeting Abstract

Exosomes in intercellular communication and implications for osteoarthritis

Asghar, S., Litherland, G. J., Lockhart, J. C., Goodyear, C. S. & Crilly, A., 1 Jan 2020, In : Rheumatology. 59, 1, p. 57-68 12 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2019

Differential effects of exosomes derived from separate osteoarthritis synovial compartments: implications for erosive cartilage disease

Asghar, S., Litherland, G., Meek, D., Cole, J., Lockhart, J., Goodyear, C. S. & Crilly, A., 30 Apr 2019, In : Osteoarthritis and Cartilage. 27, S1, p. S192 1 p., 260.

Research output: Contribution to journalMeeting Abstract

1 Citation (Scopus)

Enhanced airway smooth muscle relaxation via proteinase activated receptor 2

Black, K., MacKenzie, A., Dunning, L., Crilly, A., Brzeszczynska, J., McGarvey, L., Thornbury, K., Goodyear, C. S., Lockhart, J. C. & Litherland, G. J., 22 Nov 2019, In : Irish Journal of Medical Science. 188, SUPPL 10, p. 286-286 1 p.

Research output: Contribution to journalMeeting Abstract

Healthy primary epithelial cells show an elevated inflammatory response to bacterial stimulus compared to COPD cells

Carson, S. A., Reihill, J. A., Fulton, C. R., McGarvey, L. P., Lundy, F. T., Crilly, A. & Thornbury, K. D., 1 Apr 2019, In : The FASEB Journal. 33, Supplement 1, 127.7.

Research output: Contribution to journalMeeting Abstract

Proteinase activated receptor 2 (PAR2) modulation of murine airway function

Black, K., MacKenzie, A., Dunning, L., Crilly, A., Brzeszczyńska, J., McGarvey, L., Thornbury, K., Goodyear, C. S., Lockhart, J. & Litherland, G., 10 Sep 2019.

Research output: Contribution to conferencePoster

Open Access
File
2 Downloads (Pure)

Proteinase activated receptor 2 modulates expression of autophagy markers in murine lungs

McCallum, K., Dunning, L., McGarvey, L., Hollywood, M., Goodyear, C. S., Brzeszczynska, J., Crilly, A., Lockhart, J. C. & Litherland, G. J., 22 Nov 2019, In : Irish Journal of Medical Science. 188, SUPPL 10, p. S270-S270 1 p., 2.6.

Research output: Contribution to journalMeeting Abstract

Understanding PAR2 matriptase ENaC crosstalk in the lung: implications for COPD

Bailo, M., Dunning, L., Brzeszczynska, J., Martin, S. L., Sergeant, G. P., Goodyear, C. S., Litherland, G. J., Lockhart, J. C. & Crilly, A., 30 Nov 2019, In : Irish Journal of Medical Science. 188, SUPPL 10, p. 268-269 2 p.

Research output: Contribution to journalMeeting Abstract

2018

Assessment of the effects of exercise on a murine model of OA

Huesa, C., Dunning, L., Macdougall, K., Ortiz, A., Villaluz, M. M., Fegen, M., Crilly, A., Litherland, G., MacKenzie, A., van't Hof, R., Goodyear, C. & Lockhart, J., 30 Apr 2018, In : Osteoarthritis and Cartilage. 26, Supplement 1, p. s68 1 p.

Research output: Contribution to journalMeeting Abstract

Healthy primary epithelial cells show an elevated inflammatory response to bacterial stimulus compared to COPD cells

Carson, S., Reihill, J. A., Fulton, C. R., McGarvey, L. P., Lundy, F. T., Crilly, A., Thornbury, K. D. & Martin, S. L., 8 Oct 2018, In : Irish Journal of Medical Science. 187, Supplement 8, p. S271-S271 1 p.

Research output: Contribution to journalMeeting Abstract

Inhibition of ENaC activity by novel peptide trypsin-like inhibitors derived from amphibian skin secretions

Carroll, E. L., Douglas, L. E. J., Reihill, J. A., Zhou, M., Chen, T., McGarvey, L. P., Lundy, F. T., Hollywood, M. A., Crilly, A., Lockhart, J. C. & Martin, S. L., Aug 2018, In : Irish Journal of Medical Science. 187, Supplement 8, p. S250-S251 2 p.

Research output: Contribution to journalMeeting Abstract

Isolation and characterisation of exosomes from human primary bronchial epithelial cells

Lockhart, J., Downey, N., McGarvey, L., Martin, L., Crilly, A., Reihill, J. & Lundy, F., 2018, In : Irish Journal of Medical Science. 187, Supplement 8, p. S252-S252 1 p.

Research output: Contribution to journalMeeting Abstract

Proteinase activated receptor 2 (PAR2) modulation of airway smooth muscle function

Black, K., MacKenzie, A., Dunning, L., Crilly, A., McGarvey, L., Thornbury, K., Goodyear, C., Lockhart, J. & Litherland, G., 8 Oct 2018, In : Irish Journal of Medical Science. 187, Supplement 8, p. S249-S249 1 p.

Research output: Contribution to journalMeeting Abstract

Open Access
File
14 Downloads (Pure)

Rheumatic disease: protease-activated receptor-2 in synovial joint pathobiology

McCulloch, K., McGrath, S., Huesa, C., Dunning, L., Litherland, G., Crilly, A., Hultin, L., Ferrell, W. R., Lockhart, J. & Goodyear, C., 23 May 2018, In : Frontiers in Endocrinology. 9, 257.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

The synovial secretome contributes to cartilage pathology in osteoarthritis: a role for exosomes

Asghar, S., Litherland, G., Meek, D., Goodyear, C., Lockhart, J. & Crilly, A., 30 Apr 2018, In : Osteoarthritis and Cartilage. 26, Supplement 1, p. s131-s132 2 p., 248.

Research output: Contribution to journalMeeting Abstract

2017

The synovial secretome contributes to cartilage pathology in osteoarthritis (OA): an Exosome Study

Asghar, S., Litherland, G., Meek, D., Goodyear, C., Lockhart, J. & Crilly, A., 5 Dec 2017, (Accepted/In press).

Research output: Contribution to conferencePoster

2016

Evaluating the impact of protease activated receptor 2 (PAR2) gene disruption on T regulatory cell biology

Crilly, A., Cochrane, D., Plevin, R., Ferrell, W. R., McInness, I. B., Goodyear, C. & Lockhart, J., 8 Dec 2016.

Research output: Contribution to conferencePoster

Open Access

Proteinase-activated Receptor 2: Potential Role in Osteoarthritic Entheseal Pathology

Ortiz, A., Dunning, L., Huesa, C., Ferrell, W. R., McInnes, I. B., Lockhart, J., Millar, N. L., Goodyear, C. S. & Crilly, A., 27 Oct 2016, In : Orthopaedic Proceedings. 98-B, Suppl. 16

Research output: Contribution to journalMeeting Abstract

Open Access

Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology

Huesa, C., Ortiz, A. C., Dunning, L., McGavin, L., Bennett, L., McIntosh, K., Crilly, A., Kurowska-Stolarska, M., Plevin, R., van 't Hof, R. J., Rowan, A. D., McInnes, I. B., Goodyear, C. S., Lockhart, J. C. & Ferrell, W. R., 11 Oct 2016, In : Annals of the Rheumatic Diseases. 75, 11, p. 1989-1997

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)
2015

Differential Inflammatory Profile in Experimental Models of Arthritis

Ortiz, A. C., Crilly, A., Dunning, L., Huesa, C., Goodyear, C. S., Lockhart, J. C., Ferrell, W. R. & McInnes, I. B., Oct 2015, In : Arthritis & Rheumatology. 67, 1139.

Research output: Contribution to journalMeeting Abstract

Open Access
2013

Proteinase-activated receptor-2 modulates human macrophage differentiation and effector function

Steven, R., Crilly, A., Lockhart, J. C., R. Ferrell, W. & McInnes, I. B., Dec 2013, In : Innate Immunity. 19, 6, p. 663-72 10 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2012

Immunomodulatory role of proteinase-activated receptor-2

Crilly, A., Palmer, H., Nickdel, M. B., Dunning, L., Lockhart, J. C., Plevin, R., Mcinnes, I. B. & Ferrell, W. R., May 2012, In : Annals of the Rheumatic Diseases. 71, 9, p. 1559-1566 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

PAR(2) expression in peripheral blood monocytes of patients with rheumatoid arthritis

Crilly, A., Burns, E., Nickdel, M. B., Lockhart, J. C., Perry, M. E., Ferrell, P. W., Baxter, D., Dale, J., Dunning, L., Wilson, H., Nijjar, J. S., Gracie, J. A., Ferrell, W. R. & McInnes, I. B., Jun 2012, In : Annals of the Rheumatic Diseases. 71, 6, p. 1049-1054

Research output: Contribution to journalArticle

12 Citations (Scopus)

PAR-2 activation inhibits human osteoclast differentiation

McGavin, L., Freeburn, R., Crilly, A., Ferrell, W. R., Goodyear, C. S. & Lockhart, J. C., Sep 2012, In : Immunology. 137, S1, p. 231-231

Research output: Contribution to journalMeeting Abstract

2011

Phosphodiesterase 4 (PDE4) regulation of proinflammatory cytokine and chemokine release from rheumatoid synovial membrane

Crilly, A., Robertson, S. E., Reilly, J. H., Gracie, J. A., Lai, W-Q., Leung, B. P., Life, P. F. & McInnes, I. B., Jun 2011, In : Annals of the Rheumatic Diseases. 70, 6, p. 1130-1137 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)