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Personal profile

Overview

My research is focused at studying the effects of nanovibrational stimulation on immune cells. Just like all mammal cells, immune cells are also responsive to mechanical forces applied on them. Altered physical parameters in disease states have shown to enhance immune cell recruitment and activation, resulting in inflammation. This inflammation can be benefitial short term as the combination of the chemical and mechanical stimuli enhances the immune responses. However, since the scarred tissues and damaged organs have permanent alterations of their physical properties ( e.g. increased Young's modulus), such mechanical perturbations could result in persiting inflammation and chronic disease states. 

The aim of the project is to see if nanovibrational stimualtion can be used as a method for the controlled alteration of immune cell behavoiur. Such stimulation has been susseful for controlling differentiation of mesenchymal stem cells into bone. If immune cells are responsive to such stimulation, then this can have therapeutic benefits in a variety of immune-related disorders. One of the autoimune disorders that could benefit from such stimulation is Alopecia areata, which is a disease caused by immune cells recruiting around the hair follicles and inhibiting the hair growth. Topically altering such recrutiment using a combination of chemical and nanovirbational stimuli, could result in relief of symptoms and succesful treatment of this disease.

External positions

Technician , West of Scotland Specialist Virology Centre

Jun 2016Sep 2016

Trainee Biomedical Scientist, Queen Elizabeth University Hospital

Jan 2016Jun 2016

Trainee Biologist, Laiko General Hospital of Athens

Jun 2014Aug 2014

Keywords

  • Q Science (General)
  • Mechanobiology
  • Immunology
  • Nanokick
  • Alopecia areata
  • Biomedical Research

Fingerprint Dive into the research topics where Teontor Simakou is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Alopecia Areata Medicine & Life Sciences
Alopecia Medicine & Life Sciences
Hair Follicle Medicine & Life Sciences
Scalp Medicine & Life Sciences
Autoimmunity Medicine & Life Sciences
Coinfection Medicine & Life Sciences
Hair Medicine & Life Sciences
Autoimmune Diseases Medicine & Life Sciences

Activities 2016 2019

Smashing Science Festival, UWS Lanarkshire campus

Teontor Simakou (Invited speaker)
13 Jun 2019

Activity: Participating in or organising an eventParticipation in workshop, seminar, course

UWS Learning, Teaching and Research Conference 2019

Teontor Simakou (Speaker)
26 Jun 201927 Jun 2019

Activity: Participating in or organising an eventParticipation in conference

Super Science Festival

Teontor Simakou (Invited speaker), Lin Khoo (Speaker)
13 Feb 2019

Activity: Participating in or organising an eventParticipation in workshop, seminar, course

Smashing Science Festival, UWS Lanarkshire campus

Alicia Ware (Speaker), Teontor Simakou (Speaker), Kiri Rodgers (Speaker)
13 Jun 2019

Activity: Participating in or organising an eventParticipation in workshop, seminar, course