Research Output per year
My research is focused at studying the effects of nanovibrational stimulation on immune cells. Just like all mammal cells, immune cells are also responsive to mechanical forces applied on them. Altered physical parameters in disease states have shown to enhance immune cell recruitment and activation, resulting in inflammation. This inflammation can be benefitial short term as the combination of the chemical and mechanical stimuli enhances the immune responses. However, since the scarred tissues and damaged organs have permanent alterations of their physical properties ( e.g. increased Young's modulus), such mechanical perturbations could result in persiting inflammation and chronic disease states.
The aim of the project is to see if nanovibrational stimualtion can be used as a method for the controlled alteration of immune cell behavoiur. Such stimulation has been susseful for controlling differentiation of mesenchymal stem cells into bone. If immune cells are responsive to such stimulation, then this can have therapeutic benefits in a variety of immune-related disorders. One of the autoimune disorders that could benefit from such stimulation is Alopecia areata, which is a disease caused by immune cells recruiting around the hair follicles and inhibiting the hair growth. Topically altering such recrutiment using a combination of chemical and nanovirbational stimuli, could result in relief of symptoms and succesful treatment of this disease.
Technician , West of Scotland Specialist Virology CentreJun 2016 → Sep 2016
Trainee Biomedical Scientist, Queen Elizabeth University HospitalJan 2016 → Jun 2016
Trainee Biologist, Laiko General Hospital of AthensJun 2014 → Aug 2014
- Q Science (General)
- Alopecia areata
- Biomedical Research
Research output: Contribution to journal › Review article
Activities per year
Activity: Participating in or organising an event › Participation in conference