If you made any changes in Pure these will be visible here soon.

Personal profile

Area of academic expertise - outline

  • Drug Discovery from different natural sources incluiding marine and terrestrial organisms. Special emphasis is given to deep Sea and hyper-arid desert microbes in addition to microbial endophytes.
  • Structure elucidation of natural products using advanced one- and two-dimentional NMR and different High resolution MS techniques.
  • Applying different microbiological approaches such as OSMAC, microbial co-culture, and epigenetic modifiers for induction and isolation of novel microbial secondary metabolites from “cryptic gene clusters”.
  • Purification of complex mixtures of natural products using diverse chromatographic approaches mainly preparative HPLC and other chromatographic techniques such as VLC, SEC, SPE, and flash system.
  • GCMS analysis of volatile organic compounds from micro-organisms.

Current research activities

  • Isolation and characterization of bioactive natural products from hyper-arid Desert novel Actinomycetes
  • Isolation and characterization of bioactive natural products from marine endophytic fungi.
  • Microbial co-culture for induction of new secondary metabolites.
  • Optimization of fungal fermentation for Biofuel production.
  • Isolation of targeted bioactive plant natural products


Desired research direction

  • The Discovery of microbial natural products with potential for treatment of Neglected Tropical diseases, HIV and HCV, solid tumours, and senolytic agents.
  • The discovery of biofuel-producing fungi with potential industrial scale.



Target collaborative companies

  • Big and small Pharmaceutical companies
  • Big Research Institutes
  • Academic institutes in the UK, EU and Middle East



External positions

Honorary Research Fellow, University of Aberdeen

1 Oct 201530 Sep 2020


  • QD Chemistry
  • Microbial Natural Product Chemistry
  • Structure elucidation of natural products

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Streptomyces Medicine & Life Sciences
Endophytes Medicine & Life Sciences
Biological Products Medicine & Life Sciences
Metabolites Chemical Compounds
Diketopiperazines Medicine & Life Sciences
Fungi Medicine & Life Sciences
Indian Ocean Medicine & Life Sciences
Actinobacteria Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2007 2019

Candelariella vitellina extract triggers in vitro and in vivo cell death through induction of apoptosis: a novel anticancer agent

El-Garawani, I. M., Elkhateeb, W. A., Zaghlol, G. M., Almeer, R. S., Ahmed, E. F., Rateb, M. E. & Abdel Moneim, A. E. 7 Mar 2019 In : Food and Chemical Toxicology. 127, p. 110-119 10 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
Cell Death
Inhibitory Concentration 50

Screening for fusarium antagonistic bacteria from contrasting niches designated the endophyte bacillus halotolerans as plant warden against fusarium

Slama, H. B., Cherif-Silini, H., Chenari Bouket, A., Qader, M., Silini, A., Yahiaoui, B., Alenezi, F. N., Luptakova, L., Triki, M. A., Vallat, A., Oszako, T., Rateb, M. E. & Belbahri, L. 11 Jan 2019 In : Frontiers in Microbiology. 9, 24 p., 3236

Research output: Contribution to journalArticle

Open Access

Asenjonamides A-C, antibacterial metabolites isolated from Streptomyces asenjonii strain KNN 42.f from an extreme-hyper arid Atacama Desert soil

Abdelkader, M. S. A., Philippon, T., Asenjo, J. A., Bull, A. T., Goodfellow, M., Ebel, R., Jaspars, M. & Rateb, M. E. 23 Jan 2018 In : The Journal of Antibiotics.

Research output: Contribution to journalArticle

Open Access

Balanites aegyptiaca ameliorates insulin secretion and decreases pancreatic apoptosis in diabetic rats: rle of SAPK/JNK pathway

Hassanin, K. M. A., Mahmoud, M. O., Hassan, H. M., Abdel-Razik, A-R. H., Aziz, L. N. & Rateb, M. E. 1 Jun 2018 In : Biomedicine & Pharmacotherapy. 102, p. 1084 - 1091

Research output: Contribution to journalArticle

Open Access
MAP Kinase Signaling System
JNK Mitogen-Activated Protein Kinases

Characterization of natural bioactive compounds produced by isolated bacteria from compost of aromatic plants

El-Helw, N. O., El-Gendy, A. O., El-Gebaly, E., Hassan, H. M., Rateb, M. E. & El-Nesr, K. A. 24 Aug 2018 In : Journal of Applied Microbiology.

Research output: Contribution to journalArticle

Liquid Chromatography
Mass Spectrometry
Gram-Positive Bacteria

Activities 2000 2018

Journal of Applied Microbiology (Journal)

Rateb, M. (Peer reviewer)
2018 → …

Activity: Publication peer-review

Biomedicine & Pharmacotherapy (Journal)

Rateb, M. (Peer reviewer)
2018 → …

Activity: Publication peer-review

30th International Symposium on the Chemistry of Natural Products

Rateb, M. (Speaker), Burgio, G. (Participant)
25 Nov 201829 Nov 2018

Activity: Participation in conference

microbiological research (Journal)

Rateb, M. (Peer reviewer)
2018 → …

Activity: Publication peer-review

Ist Euroindoamerican Natural Products Meeting

Rateb, M. (Speaker), Thissera, B. (Participant)
29 May 20181 Jun 2018

Activity: Participation in conference


Majed Bawazeer


Gaia Burgio

Bathini Thissera

Liquid Chromatography
Gas Chromatography-Mass Spectrometry