Lynette Dunning

Research Output

Research Output per year

2003 2020

• 16 Meeting Abstract
• 10 Article
• 5 Poster
• 1 Conference contribution
• 2 More
  • 1 Abstract
  • 1 Review article

Research Output per year

Research Output per year

Search results

• 2020

  Murine airway bronchodilation via Proteinase Activated Receptor 2

  Black, K., MacKenzie, A., Dunning, L., Crilly, A., Brzeszczyńska, J., McGarvey, L., Thornbury, K., Goodyear, C. S., Lockhart, J. C. & Litherland, G. J., 28 Oct 2020, In: European Respiratory Journal. 56, Supplement 64, 1895.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • PAR-2 Receptor
  • Smooth Muscle
  • Muscle Relaxation
  • Chronic Obstructive Pulmonary Disease
  • Trypsin

• Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells

  Bailo, M., Dunning, L., Brzeszczynska, J., McIntosh, K., Plevin, R., Martin, S. L., Sergeant, G. P., Goodyear, C. S., Litherland, G. S., Lockhart, J. C. & Crilly, A., 28 Oct 2020, In: European Respiratory Journal. 56, Supplement 64, 2292.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • PAR-2 Receptor
  • AZ8838
  • Epithelial Cells
  • Cytokines
  • Chronic Obstructive Pulmonary Disease

• Regulation of lung autophagy by proteinase-activated receptor 2 activation

  Mccallum, K., Dunning, L., Mcgarvey, L., Hollywood, M., Brzeszczynska, J., Goodyear, C., Lockhart, J., Crilly, A. & Litherland, G., 15 Apr 2020, In: ERJ Open Research. 6, suppl 5, 75.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File

  • PAR-2 Receptor
  • Autophagy
  • Lung
  • Chronic Obstructive Pulmonary Disease
  • Premature Aging

• Repeated exposure to hydrogen peroxide enhances TGF-ß and LPS dependent inflammatory responses in BEAS-2B cells

  Tarhini, F., Dunning, L., Crilly, A., Brzeszczyńska, J., McGarvey, L., Thornbury, K., Goodyear, C. S., Lockhart, J. C. & Litherland, G. J., 28 Oct 2020, In: European Respiratory Journal. 56, Supplement 64, 607.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Hydrogen Peroxide
  • Interleukin-8
  • Chronic Obstructive Pulmonary Disease
  • Interleukin-6
  • Oxidants
• 2019

  Enhanced airway smooth muscle relaxation via proteinase activated receptor 2

  Black, K., MacKenzie, A., Dunning, L., Crilly, A., Brzeszczynska, J., McGarvey, L., Thornbury, K., Goodyear, C. S., Lockhart, J. C. & Litherland, G. J., 22 Nov 2019, In: Irish Journal of Medical Science. 188, SUPPL 10, p. 286-286 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File
  1 Downloads (Pure)

• PAR2 accelerates osteoarthritis-like joint changes in a murine model of post-traumatic osteoarthritis

  Goodyear, C., McCulloch, K., Huesa, C., Dunning, L., van 't Hof, R. & Lockhart, J., 27 Jun 2019, In: Annals of the Rheumatic Diseases. 78, Issue Suppl 2, p. 110-110 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • mouse F2rl1 protein
  • PAR-2 Receptor
  • Tibial Meniscus
  • Osteophyte
  • Osteoarthritis

• Proteinase activated receptor-2 induced autophagy dysregulation

  McCallum, K., Dunning, L., McGarvey, L., Hollywood, M., Brzeszczynska, J., Crilly, A., Lockhart, JC. & Litherland, GJ., 12 Nov 2019, In: THORAX. 74, Supplement 1, 1 p., A49.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File

• Proteinase activated receptor 2 modulates expression of autophagy markers in murine lungs

  McCallum, K., Dunning, L., McGarvey, L., Hollywood, M., Goodyear, C. S., Brzeszczynska, J., Crilly, A., Lockhart, J. C. & Litherland, G. J., 22 Nov 2019, In: Irish Journal of Medical Science. 188, SUPPL 10, p. S270-S270 1 p., 2.6.

  Research output: Contribution to journal › Meeting Abstract › peer-review

• Understanding PAR2 matriptase ENaC crosstalk in the lung: implications for COPD

  Bailo, M., Dunning, L., Brzeszczynska, J., Martin, S. L., Sergeant, G. P., Goodyear, C. S., Litherland, G. J., Lockhart, J. C. & Crilly, A., 30 Nov 2019, In: Irish Journal of Medical Science. 188, SUPPL 10, p. 268-269 2 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2018

  Assessment of the effects of exercise on a murine model of OA

  Huesa, C., Dunning, L., Macdougall, K., Ortiz, A., Villaluz, M. M., Fegen, M., Crilly, A., Litherland, G., MacKenzie, A., van't Hof, R., Goodyear, C. & Lockhart, J., 30 Apr 2018, In: Osteoarthritis and Cartilage. 26, Supplement 1, p. s68 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Pathology
  • Tibial Meniscus
  • Surgery
  • Osteoarthritis
  • Bone

• Investigating the matriptase-PAR2-ENaC axis in lung epithelial cells: potential role in COPD pathogenesis

  Lockhart, J., Bailo, M., McCallum, K., Dunning, L., Stankovic, M., Reihill, J., Sergeant, G., Goodyear, C. & Litherland, G., 8 Oct 2018, In: Irish Journal of Medical Science. 187, Supplement 8, p. S249 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File

  • matriptase
  • PAR-2 Receptor
  • Chronic Obstructive Pulmonary Disease
  • Epithelial Cells
  • Lung

• Proteinase activated receptor 2 (PAR2) modulation of airway smooth muscle function

  Black, K., MacKenzie, A., Dunning, L., Crilly, A., McGarvey, L., Thornbury, K., Goodyear, C., Lockhart, J. & Litherland, G., 8 Oct 2018, In: Irish Journal of Medical Science. 187, Supplement 8, p. S249-S249 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File

  • PAR-2 Receptor
  • Smooth Muscle
  • Chronic Obstructive Pulmonary Disease
  • Lung
  • Muscle Tonus
  45 Downloads (Pure)

• Proteinase activated receptor-2 and autophagy regulation in airway epithelia cells

  McCallum, K., Bailo, M., Dunning, L., Stankovic, M., McGarvey, L., Hollywood, M., Goodyear, C. S., Crilly, A., Lockhart, J. C. & Litherland, G. J., 8 Oct 2018, In: Irish Journal of Medical Science. 187, Supplement 8, p. S272-S273 2 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  File

  • PAR-2 Receptor
  • Autophagy
  • Epithelium
  • Lung
  • Premature Aging
• 2016

  Proteinase-activated Receptor 2: Potential Role in Osteoarthritic Entheseal Pathology

  Ortiz, A., Dunning, L., Huesa, C., Ferrell, W. R., McInnes, I. B., Lockhart, J., Millar, N. L., Goodyear, C. S. & Crilly, A., 27 Oct 2016, In: Orthopaedic Proceedings. 98-B, Suppl. 16

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access
• 2015

  Differential Inflammatory Profile in Experimental Models of Arthritis

  Ortiz, A. C., Crilly, A., Dunning, L., Huesa, C., Goodyear, C. S., Lockhart, J. C., Ferrell, W. R. & McInnes, I. B., Oct 2015, In: Arthritis & Rheumatology. 67, 1139.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

• Microrna Biomarker Signature in Osteoarthritis

  Bennett, L. A., Coleman, T., Ferrell, W., Lockhart, J., Huesa, C., Dunning, L., Jones, B., Blyth, M., McInnes, I. B., Kurowska-Stolarska, M. & Goodyear, C. S., Oct 2015, In: Arthritis & Rheumatology. 67, 2398.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access