Kate Tedford

Professor

School of Computing, Engineering and Physical Sciences

Accepting PhD Students

PhD projects

Site directed delivery of bioactive small molecules. Optimising the colonisation resistance barrier in the gut

Willing to speak to media

Research output per year

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Personal profile

Area of academic expertise - outline

Prof Tedford's research concentrates on the effect of colonic propionate on appetite regulation, body weight and insulin sensitivity. Obesity and its associated diseases, including type 2 diabetes, coronary heart disease and certain cancers, are major public health challenges for the 21st century. The objective of her research is to identify an intervention that decreases appetite, prevents weight gain and reduces insulin resistance, and which is applicable at a public health level. Catriona also has interests in the development of novel tracers for characterisation of colon bacterial metabolism and novel biomarkers of the nitrosation potential of the GI tract.

Current research activities

Effect of small molecules on gut metabolism, controlling obesity and CDifficile infection

Desired research direction

Biosensors, nutritional biochemistry, organic chemistry, analytical chemistry

Target collaborative companies

Nutrition, food and drink companies, sensor technology companies

Current teaching activities and interests

Analytical techniques, biological chemistry, forensic investigation, molecular recognition, drug metabolism and behaviour, forensic biology, stereochemistry, asymmetric synthesis

External positions

External Verifier, Scottish Qualifications Agency

2009 → …

Keywords

QD Chemistry
Biosensors, nutritional biochemistry, organic chemistry, analytical chemistry

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Research Output

28 Article
4 Meeting Abstract
1 Chapter
1 Poster

Moderate intensity exercise training combined with inulin-propionate ester supplementation increases whole body resting fat oxidation in overweight women

Malkova, D., Polyviou, T., Rizou, E., Gerasimidis, K., Chambers, E. S., Preston, T., Tedford, C. M., Frost, G. & Morrison, D. J., 31 Mar 2020, In : Metabolism - Clinical and Experimental. 104, 4 p., 154043.

Research output: Contribution to journal › Article

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised crossover trial

Chambers, E. S., Byrne, C. S., Morrison, D. J., Murphy, K. G., Preston, T., Tedford, M. C., Garcia-Perez, I., Fountana, S., Serrano-Contreras, J. I., Holmes, E., Roberts, J. F., Reynolds, C. J., Boyton, R. J., Altmann, D. M., McDonald, J. A. K., Marchesi, J. R., Akbar, A. N., Riddell, N. E., Wallis, G. A. & Frost, G., 5 Jul 2019, In : Gut. 68, 8, p. 1430-1438 9 p.

Research output: Contribution to journal › Article

Open Access

File

28 Citations (Scopus)

129 Downloads (Pure)

Drivers of Clostridioides difficile hypervirulent ribotype 027 spore germination, vegetative cell growth and toxin production in vitro

Yuille, S., MacKay, W. G., Morrison, D. J. & Tedford, M. C., 9 Nov 2019, In : Clinical Microbiology and Infection.

Research output: Contribution to journal › Article

Effects of inulin propionate ester incorporated into palatable food products on appetite and resting energy expenditure: a randomised crossover study

Byrne, C. S., Chambers, E. S., Preston, T., Tedford, C., Brignardello, J., Garcia-Perez, I., Holmes, E., Wallis, G. A., Morrison, D. J. & Frost, G. S., 16 Apr 2019, In : Nutrients. 11, 4, 861.

Research output: Contribution to journal › Article

Open Access

File

1 Citation (Scopus)

101 Downloads (Pure)

The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease

Chambers, E. S., Byrne, C. S., Rugyendo, A., Morrison, D. J., Preston, T., Tedford, M. C., Bell, J. D., Thomas, E. L., Akbar, A. N., Riddell, N. E., Sharma, R., Thursz, M. R., Manousou, P. & Frost, G., 28 Feb 2019, In : Diabetes, Obesity and Metabolism. 21, 2, p. 372-376 5 p.

Research output: Contribution to journal › Article

Open Access

File