Kate Tedford — The UWS Academic Portal

Personal profile

Area of academic expertise - outline

Prof Tedford's research concentrates on the effect of colonic propionate on appetite regulation, body weight and insulin sensitivity. Obesity and its associated diseases, including type 2 diabetes, coronary heart disease and certain cancers, are major public health challenges for the 21st century. The objective of her research is to identify an intervention that decreases appetite, prevents weight gain and reduces insulin resistance, and which is applicable at a public health level. Catriona also has interests in the development of novel tracers for characterisation of colon bacterial metabolism and novel biomarkers of the nitrosation potential of the GI tract.

Current research activities

Effect of small molecules on gut metabolism, controlling obesity and CDifficile infection

Desired research direction

Biosensors, nutritional biochemistry, organic chemistry, analytical chemistry

Target collaborative companies

Nutrition, food and drink companies, sensor technology companies

Current teaching activities and interests

Analytical techniques, biological chemistry, forensic investigation, molecular recognition, drug metabolism and behaviour, forensic biology, stereochemistry, asymmetric synthesis

External positions

External Verifier, Scottish Qualifications Agency

2009 → …

Keywords

QD Chemistry
Biosensors, nutritional biochemistry, organic chemistry, analytical chemistry

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Propionates Medicine & Life Sciences

Dissolved oxygen Chemical Compounds

Inulin Medicine & Life Sciences

Phosphorescence Chemical Compounds

Dissolved oxygen sensors Chemical Compounds

Volatile Fatty Acids Medicine & Life Sciences

Esters Medicine & Life Sciences

Oxygen Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1990 2019

23 Article
4 Meeting Abstract
1 Chapter
1 Poster

The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease

Chambers, E. S., Byrne, C. S., Rugyendo, A., Morrison, D. J., Preston, T., Tedford, M. C., Bell, J. D., Thomas, E. L., Akbar, A. N., Riddell, N. E., Sharma, R., Thursz, M. R., Manousou, P. & Frost, G. 28 Feb 2019 In : Diabetes, Obesity and Metabolism. 21, 2, p. 372-376 5 p.

Research output: Contribution to journal › Article

Inulin

Propionates

Dietary Supplements

Esters

Liver

The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro

Pingitore, A., Chambers, E. S., Hill, T., Maldonado, I. R., Liu, B., Bewick, G., Morrison, D. J., Preston, T., Wallis, G. A., Tedford, C., Castañera González, R., Huang, G. C., Choudhary, P., Frost, G. & Persaud, S. J. 28 Feb 2017 In : Diabetes, Obesity and Metabolism. 19, 2, p. 257-265 9 p.

Research output: Contribution to journal › Article

Open Access

File

Volatile Fatty Acids

Propionates

Insulin

Diet

Glucose

Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods

Byrne, C. S., Chambers, E. S., Alhabeeb, H., Chhina, N., Morrison, D. J., Preston, T., Tedford, C., Fizpatrick, J., Irani, C., Busza, A., Garcia-Perez, I., Fountana, S., Holmes, E., Goldstone, A. P. & Frost, G. S. 11 May 2016 In : The American Journal of Clinical Nutrition.

Research output: Contribution to journal › Article

Open Access

Propionates

Reward

Food

Volatile Fatty Acids

Feeding Behavior

Randomised clinical study: inulin short-chain fatty acid esters for targeted delivery of short-chain fatty acids to the human colon

Polyviou, T., Macdougall, K., Chambers, E. S., Viardot, A., Psichas, A., Jawaid, S., Harris, H. C., Edwards, C. A., Simpson, L., Murphy, K. G., Zac-Varghese, S. E. K., Blundell, J. E., Dhillo, W. S., Bloom, S. R., Frost, G. S., Preston, T., Tedford, C. & Morrison, D. J. 4 Sep 2016 In : Alimentary Pharmacology & Therapeutics. 44, 7, p. 662-672

Research output: Contribution to journal › Article

Open Access

Inulin

Volatile Fatty Acids

Propionates

Colon

Esters